The Effects of Microcurrents on Inflammatory Reaction Induced by Ultraviolet Irradiation

Lee, Jeong-Woo; Yoon, Se-Won; Kim, Tae-Hee; Park, Soo-Ji

doi:10.1589/jpts.23.693

Cited by 8 publications

(8 citation statements)

References 15 publications

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“…Esses resultados corroboram com Kaur et al (2011) que estudaram edema em orelha de rato e observaram a ação da microcorrente na redução da resposta inflamatória. A microcorrente é apontada como promotora de resposta anti-inflamatória (COOK et al, 1994;LEE et al, 2011) melhorando o reparo de tecidos lesionados. A. montana apresenta também importante ação anti-inflamatória quando utilizada em formulação homeopática ou não, em animais e seres humanos (CONFORTI et al, 2007;KAROW et al, 2008;KAWAKAMI et al, 2011;SOUSA et al, 2011;CASSU et al, 2011).…”

Section: Resultsunclassified

Microcorrente E Arnica Montana Na Cicatrização Em Ratos

Esquisatto

2020

REP

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A cicatrização de feridas é um problema de saúde pública e, por isso, o processo de reparo tecidual tem merecido atenção de pesquisadores, principalmente no que se refere aos fatores que o retardam ou dificultam. A aplicação de microcorrente em lesões teciduais desempenha papel fundamental no processo de cicatrização sendo capaz de restaurar o fluxo elétrico na região da lesão, além de contribuir para diminuição da contaminação bacteriana. Também a utilização de plantas medicinais como Arnica montana é de grande interesse, pois esta espécie possui a propriedade de acelerar o processo de cicatrização quando utilizada topicamente sobre a região afetada. Neste sentido, o presente estudo visa analisar os efeitos da estimulação com microcorrente associada ou não à aplicação tópica de A. montana em lesões incisionais na pele de ratos. Trinta e seis animais, de 90 dias, com 250g, foram divididos aleatoriamente em (n=3): (C) sem tratamento; (MC) tratado com microcorrente (10 µA/2 min); (A) tratado com aplicação tópica de gel contendo A. montana; (A+MC) tratado com aplicação tópica de gel contendo A. montana + microcorrente (10 µA/2 min).. Amostras foram coletadas dos animais eutanasiados no 2º, 6º e 10º dia após a lesão cirúrgica para análise histomorfométrica: quantificação de infiltrado inflamatório, vasos sanguíneos, fibroblastos e porcentagem da área de colágeno. Para análise estatística foi utilizado ANOVA Two-way e pós-teste de Tukey (média±erro padrão). As terapias combinadas ou não, diminuíram a quantidade de infiltrado inflamatório e aumentaram o número de fibroblastos, colágeno e vasos sanguíneos durante o período experimental. A associação da aplicação de microcorrente e A. montana foi efetiva no reparo tecidual de lesões incisionais na pele do dorso de ratos, controlando a inflamação, favorecendo a fibroplasia, colagênese e angiogênese.

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Section: Resultsunclassified

Microcorrente E Arnica Montana Na Cicatrização Em Ratos

Esquisatto

2020

REP

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“…Using the PB, this study evaluated the Proxywave ® , which consists of 10 MHz of AC and 0.5 V DC. Proxywave ® induces a microcurrent of 100 µA, a signal similar to a biocurrent, which is safe for human applications [19]. The brush is comprised of two parallel electrodes that introduce the wave directly to the teeth.…”

Section: Brushmentioning

confidence: 99%

Bioelectric Effect of a Microcurrent Toothbrush on Plaque Removal

Lee

2021

IJERPH

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This study evaluated the effectiveness of a microcurrent toothbrush (approved by the US Food and Drug Administration [FDA]), which employs a superimposed alternating and direct electric current, named as a Proxywave® technology, similar to the intensity of the biocurrent, in plaque removal and reducing gingivitis by biofilm removal through the bioelectric effect. This study enrolled 40 volunteers with gingivitis. Dental observations were made every two weeks, before and after the use of each toothbrush. We randomly assigned participants into two groups: one group used the Proxywave® toothbrush (PB) for two weeks followed by the control toothbrush (CB) for two weeks, while the other group used the CB for two weeks followed by the PB. The participants had a two-week washout period. If the toothbrush used earlier has had an effect on the bacterial flora in the oral cavity, this is to remove this effect and return it to its previous state. During each dental visit, we recorded plaque index (PI) and gingival index (GI) scores. The PI and GI scores were significantly lower in both the PB and the CB (p < 0.05). Considering the PI, there was no significant difference between the toothbrushes on all the surfaces. Considering the GI, the PB showed a significant decrease in the interproximal surface, compared to the CB (p < 0.05). The PB showed a significant decrease in the interproximal GI and had a beneficial effect in the interproximal area where the bristles could not reach. No adverse events were observed in the participants during the clinical trial. The microcurrent toothbrush is a device that can be safely used for plaque removal.

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“…Kloth noted that electrical stimulation applied to wounded skin tissues increased angiogenesis and perfusion, which raised the activity of granulation tissues and fibroblasts, thereby promoting wound healing speed 9 ) . Physical therapy approaches to wound healing include HVPCS, microcurrents, low-intensity laser, and ultrasound 10 , 11 , 12 , 13 ) . HVPCS has a monophasic twin peak pulse wave form and very short pulse duration and therefore can safely stimulate deep tissues without damage 14 ) .…”

Section: Introductionmentioning

confidence: 99%

Effects of high voltage pulsed current stimulation with a visible contraction intensity on expression of TGF-β1 and synthesis of type I collagen in wound-induced white rats

2015

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[Purpose] This study aimed to examine the expression of transforming growth factor β1 (TGF-β1) and type I collagen by applying high voltage pulsed current stimulation (HVPCS) with a visible contraction intensity to white rats with induced wounds. [Subjects] Thirty-six white rats were used for this study. HVPCS with a non-visible contraction intensity was applied to experimental group I, and HVPCS with a visible contraction intensity was applied to experimental group II. Placebo stimulation was applied to the control group. [Methods] After wounds were triggered, the intervention appropriate for each group was applied. Changes in the size of their wounds and expression of TGF- β1 and type I collagen were measured on the third, fifth, and seventh days. [Results] Comparison of the sizes of the wounds among the groups showed that the most significant decreases were found in experimental group II on the fifth and seventh days. TGF-β1 expression comparison revealed that experimental group II had the most expression on the fifth day. [Conclusion] HVPCS with a visible contraction intensity was effective in promoting wound healing by increasing expression of TGF-β1 and synthesis of type I collagen.

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The Effects of Microcurrents on Inflammatory Reaction Induced by Ultraviolet Irradiation

Cited by 8 publications

References 15 publications

Microcorrente E Arnica Montana Na Cicatrização Em Ratos

Microcorrente E Arnica Montana Na Cicatrização Em Ratos

Bioelectric Effect of a Microcurrent Toothbrush on Plaque Removal

Effects of high voltage pulsed current stimulation with a visible contraction intensity on expression of TGF-β1 and synthesis of type I collagen in wound-induced white rats

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