The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost

Abstract

Introduction: In this study, the goal was to evaluate the impact of nosocomial rotavirus gastroenteritis in pediatric patients by determining the incidence of nosocomial rotavirus gastroenteritis, the resulting duration of hospital stay, and direct cost. To our knowledge, this is the first study in Turkey that evaluates the impact of pediatric nosocomial rotavirus gastroenteritis on duration of hospital stay and calculates the direct cost. Methodology: Forty-nine patients who were diagnosed with nosocomial rotavirus gastroenteritis and hospitalized were included in the study. Nosocomial infection rates, organ systems affected by the nosocomial infections, and patients who had nosocomial rotavirus gastroenteritis were identified. A direct cost analysis of patients who were diagnosed with nosocomial rotavirus gastroenteritis was performed using copies of the invoices for the hospital bills. Results: During the study period, there were 49 cases of nosocomial rotavirus gastroenteritis. The length of hospitalization was extended, on average, by more than 6.3 days in cases of nosocomial rotavirus gastroenteritis. The cost of hospitalization for patients with nosocomial rotavirus gastroenteritis was on average 1,554 ± 2,067 US dollars, compared to a cost of only 244 ± 103 US dollars for patients who did not have nosocomial rotavirus gastroenteritis. This difference in cost was statistically significant (p < 0.05). Conclusions: Nosocomial rotavirus gastroenteritis is important because it significantly prolongs hospital stay and increases the social and economic burden of the hospitalization. Nosocomial rotavirus gastroenteritis can be reduced with prevention measures such as handwashing, isolation, and cohorting.

Serum transaminase elevation in Patients with rotavirus gastroenteritis

“…Rotavirus gastroenteritis is associated with 2-3 million hospitalizations and 600.000 deaths especially in developing countries each year among children aged less than 5 years. Nosocomial rotavirus gastroenteritis is known to prolong hospital stay and to increase cost [1]. Rotavirus infection stimulates humoral and cell-mediated immune response at mucosal level, and the virus is normally cleared by one week.…”

The Sustained Rotavirus Vaccination Impact on Nosocomial Infection, Duration of Hospital Stay, and Age: The RotaBIS Study (2005–2012)

“…In addition, data on many other parameters were systematically collected during the whole follow-up period of the RotaBIS project. These additional data are now analyzed in the present study to address further questions on the impact of the vaccine on RV-induced nosocomial infections [13], the average duration of hospital stay being for a certain period a surrogate marker for disease severity [14], a potential more pronounced age shift of RV disease after the introduction of the vaccine [15], and the sustainability of the vaccine impact (VI) over time [12]. …”