The hydrodynamic coefficient is the basis of the research on the maneuverability of underwater vehicles. In recent years, with the rapid development of underwater unmanned systems, the research on the calculation of hydrodynamic coefficient has attracted extensive attention from scholars at home and abroad. Taking an underwater vehicle as the research object to solve its hydrodynamic coefficient, three methods are used to calculate the hydrodynamic coefficient of the horizontal kinematic equation of the underwater vehicle: theoretical estimation, system identification based on actual navigation data and numerical simulation using the hydrodynamic calculation software FLUENT. In the end, the advantages, disadvantages, and applicable conditions of the three calculation methods are summarized.