State regulation of the agricultural sector is one of the main elements of increasing the efficiency of the country’s agricultural sector. The article discusses the problems of using the organizational and economic mechanism to regulate the agricultural sector in the Russian Federation, analyzes the issues of regulation of the agricultural sector in the context of the development of digitalization. State regulation of the development of the digital economy in agro-industrial sectors involves the development of the legal framework for access to information stored on the Internet of “things platforms”, the protection of the Russian segment of the Internet of things, for this it is necessary to create a closed network in the country and to solve the problems of import substitution in the context of a lack of domestic equipment. Implementation of state programs on digitalization of agriculture will be a link in the construction of the “Digital Economy of the Russian Federation”. In conclusion, priority directions for improving the mechanisms of state regulation of the agricultural sector are given.