The emergence of metal oxide nanoparticles (NPs) as a phytomedicine: A two-facet role in plant growth, nano-toxicity and anti-phyto-microbial activity

Bhattacharjee, Rahul; Kumar, Lamha; Mukerjee, Nobendu; Anand, Uttpal; Dhasmana, Archna; Preetam, Subham; Bhaumik, Samudra; Sihi, Sanjana; Pal, Sanjana; Khare, Tushar; Chattopadhyay, Soham; El‐Zahaby, Sally A.; Alexiou, Athanasios; Koshy, Eapen P.; Kumar, Vinay; Malik, Sumira; Dey, Abhijit; Proćków, Jarosław

doi:10.1016/j.biopha.2022.113658

Cited by 70 publications

(39 citation statements)

References 187 publications

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“…The synthesis of inorganic nanomaterials such as metals and metal oxides using the “green synthesis technique” has gained popularity due to its sustainability, reliability, low cost, simple procedure, large‐scale production and harmlessness. In this method, inorganic nanomaterials can be produced by using a plant or plant extract as a reducing agent to reduce the metal precursor to its elemental form at the nanoscale 24–30 …”

Section: Nanomaterialsmentioning

confidence: 99%

“…In this method, inorganic nanomaterials can be produced by using a plant or plant extract as a reducing agent to reduce the metal precursor to its elemental form at the nanoscale. [24][25][26][27][28][29][30] Inorganic nanoparticles include metals and metal oxides. Metal oxide-based inorganic nanomaterials include zinc oxide (ZnO), copper oxide (CuO), magnesium aluminium oxide (MgAl 2 O 4 ), titanium dioxide (TiO 2 ), cerium oxide (CeO 2 ), iron oxide (Fe 2 O 3 ), silicon dioxide (SiO 2 ), iron (Fe 3 O 4 ), etc.…”

Section: F I G U R Ementioning

confidence: 99%

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Nano‐biotechnology in tumour and cancerous disease: A perspective review

Soni

Bhandari

Tripathi

et al. 2023

J Cellular Molecular Medi

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In recent years, drug manufacturers and researchers have begun to consider the nanobiotechnology approach to improve the drug delivery system for tumour and cancer diseases. In this article, we review current strategies to improve tumour and cancer drug delivery, which mainly focuses on sustaining biocompatibility, biodistribution, and active targeting. The conventional therapy using cornerstone drugs such as fludarabine, cisplatin etoposide, and paclitaxel has its own challenges especially not being able to discriminate between tumour versus normal cells which eventually led to toxicity and side effects in the patients. In contrast to the conventional approach, nanoparticle-based drug delivery provides target-specific delivery and controlled release of the drug, which provides a better therapeutic window for treatment options by focusing on the eradication of diseased cells via active targeting and sparing normal cells via passive targeting. Additionally, treatment of tumours associated with the brain is hampered by the impermeability of the blood-brain barriers to the drugs, which eventually led to poor survival in the patients. Nanoparticle-based therapy offers superior delivery of drugs to the target by breaching the blood-brain barriers. Herein, we provide an overview of the properties of nanoparticles that are crucial for nanotechnology applications. We address the potential future applications

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Section: Nanomaterialsmentioning

confidence: 99%

Section: F I G U R Ementioning

confidence: 99%

Nano‐biotechnology in tumour and cancerous disease: A perspective review

Soni

Bhandari

Tripathi

et al. 2023

J Cellular Molecular Medi

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“…Besides that, other bacterial strains such as Acinetobacter sp. TW and Comamonas testosteroni I2 cause biodegradation of 4-fluoroaniline and 3-chloroaniline from polluted water [ 82 , 83 ]. Nevertheless, the highly effective outcome of bioaugmentation possesses certain limitations such as physiological parameters for the cultivation of microbial cells, and abiotic and biotic stresses (e.g., temperature, pH, lack of nutrients, phage infections, compatibility, and competitiveness) resulting in bioaugmentation failure.…”

Section: Bioaugmentation and Immobilization Of Microbial Cells With N...mentioning

confidence: 99%

Exploring Microbial-Based Green Nanobiotechnology for Wastewater Remediation: A Sustainable Strategy

Malik

Dhasmana

Preetam³

et al. 2022

Nanomaterials

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Water scarcity due to contamination of water resources with different inorganic and organic contaminants is one of the foremost global concerns. It is due to rapid industrialization, fast urbanization, and the low efficiency of traditional wastewater treatment strategies. Conventional water treatment strategies, including chemical precipitation, membrane filtration, coagulation, ion exchange, solvent extraction, adsorption, and photolysis, are based on adopting various nanomaterials (NMs) with a high surface area, including carbon NMs, polymers, metals-based, and metal oxides. However, significant bottlenecks are toxicity, cost, secondary contamination, size and space constraints, energy efficiency, prolonged time consumption, output efficiency, and scalability. On the contrary, green NMs fabricated using microorganisms emerge as cost-effective, eco-friendly, sustainable, safe, and efficient substitutes for these traditional strategies. This review summarizes the state-of-the-art microbial-assisted green NMs and strategies including microbial cells, magnetotactic bacteria (MTB), bio-augmentation and integrated bioreactors for removing an extensive range of water contaminants addressing the challenges associated with traditional strategies. Furthermore, a comparative analysis of the efficacies of microbe-assisted green NM-based water remediation strategy with the traditional practices in light of crucial factors like reusability, regeneration, removal efficiency, and adsorption capacity has been presented. The associated challenges, their alternate solutions, and the cutting-edge prospects of microbial-assisted green nanobiotechnology with the integration of advanced tools including internet-of-nano-things, cloud computing, and artificial intelligence have been discussed. This review opens a new window to assist future research dedicated to sustainable and green nanobiotechnology-based strategies for environmental remediation applications.

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“…Moreover, the antimicrobial activity of CuO-NPs has also been reported against Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis, and methicillin-resistance Staphylococcus aureus (MRSA) 9 . Recently, few reports studied the bactericidal activity of CuO-NPs which was found to generate reactive oxygen species (ROS) causing bacterial cell death 24 . The CuO-NPs size greatly affects the antibacterial activity (the smaller nanoparticles size, the higher antibacterial activity) 24 .…”

mentioning

confidence: 99%

“…Recently, few reports studied the bactericidal activity of CuO-NPs which was found to generate reactive oxygen species (ROS) causing bacterial cell death 24 . The CuO-NPs size greatly affects the antibacterial activity (the smaller nanoparticles size, the higher antibacterial activity) 24 . CuO-NPs directly bind to the bacterial cell wall, interact with the membranes' proteins that lead to membrane perforation and releasing intracellular materials 25 .…”

mentioning

confidence: 99%

Arc discharge rapid synthesis of engineered copper oxides nano shapes with potent antibacterial activity against multi-drug resistant bacteria

Elwakil

Toderas

El-Khatib

2022

Sci Rep

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Nowadays Nano metals have received an eminent compromise of attention. Even though different nanostructure of same metal maybe gives different results in wide range applications. Copper oxide (CuO-NPs) and Copper Nano wires (CuO-NWs) were prepared in controlled size via the alternating current Arc discharge process. Deionized water and argon gas were the chosen dielectric medium during the process to obtain 2 different forms of copper oxides. By changing the dielectric material from deionized water to argon gas the shape of CuO nanoparticles changed from spherical (CuO-NPs) to wires (CuO-NWS). The yield prepared depicted the purity of the prepared CuO, and their diameters were about 10 ± 5 nm and 30 ± 3 nm for CuO-NWs and CuO-NPs respectively. In vitro cytotoxic effect of the prepared CuO-NWs & CuO-NPs using human normal lung fibroblast cell line (WI-38 cells) revealed that CuO-NWs & CuO-NPs CC50 values were 458.8 and 155.6 µg/mL respectively. Both yields showed potent antibacterial activity against different multi-drug resistant Acinetobacter baumannii strains. A complete eradication of the bacterial growth was noticed after 4 Hrs incubation with CuO-NWs. Moreover, CuO-NWs showed superior antibacterial activity (with minimum inhibitory concentration reached 1.8 µg/mL) over CuO-NPs. The detailed antibacterial activity mechanism of CuO-NWs was further investigated; data proved the precipitation and adsorption of the nanoparticles on the bacterial cell surface leading to cell deformation with reactive oxygen species increment. The results explicated that the nanoparticles shape plays an essential role in the antibacterial activity. Rotational Arc discharge machine might be a promising tool to obtain various metal nanostructures with low cost and environmentally friendly with potent activity.

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The emergence of metal oxide nanoparticles (NPs) as a phytomedicine: A two-facet role in plant growth, nano-toxicity and anti-phyto-microbial activity

Cited by 70 publications

References 187 publications

Nano‐biotechnology in tumour and cancerous disease: A perspective review

Nano‐biotechnology in tumour and cancerous disease: A perspective review

Exploring Microbial-Based Green Nanobiotechnology for Wastewater Remediation: A Sustainable Strategy

Arc discharge rapid synthesis of engineered copper oxides nano shapes with potent antibacterial activity against multi-drug resistant bacteria

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