The ethnobotany of South African medicinal orchids

Chinsamy, Mayashree; Finnie, J.F.; Staden, J. Van

doi:10.1016/j.sajb.2010.09.015

Cited by 49 publications

(30 citation statements)

References 12 publications

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“…Among these, one species occurs in tropical America. Different Eulophia species have been extensively used in the traditional system of medicines in many countries ( Chinsamy et al, 2011 ; Patil and Mahajan, 2013 ; Narkhede et al, 2016 ). For instance, in India, the word Amarkand is commonly used for 30 plant species from genus Eulophia and for one species from the genus Dioscorea.…”

Section: Introductionmentioning

confidence: 99%

Vasorelaxant and Hypotensive Effects of an Ethanolic Extract of Eulophia macrobulbon and Its Main Compound 1-(4′-Hydroxybenzyl)-4,8-Dimethoxyphenanthrene-2,7-Diol

et al. 2018

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Background: Ethnopharmacological studies demonstrated the potential for Eulophia species to treat inflammation, cancer, and cardio-metabolic diseases. The aim of the study was to investigate the vasorelaxant effect of ethanolic Eulophia macrobulbon (EM) extract and its main phenanthrene on rat isolated mesenteric artery and to investigate the hypotensive effect of EM.Methods: The vasorelaxant effects of EM extract or phenanthrene and the underlying mechanisms were evaluated on second-order mesenteric arteries from Sprague Dawley rats. In addition, the acute hypotensive effect was evaluated in anesthetized rats infused with cumulative concentrations of the EM extract.Results: Both EM extract (10-4–1 mg/ml) and phenanthrene (10-7–10-4 M) relaxed endothelium-intact arteries, an effect that was partly reduced by endothelium removal (p < 0.001). A significant decrease in the relaxant effect of the extract and the phenanthrene was observed with L-NAME and apamin/charybdotoxin in endothelium-intact vessels, and with iberiotoxin in denuded vessels. SNP (sodium nitroprusside)-induced relaxation was significantly enhanced by EM extract and phenanthrene. By contrast, ODQ (1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline-1-one), 4-aminopyridine and glibenclamide (endothelium-denuded vessels) and indomethacin (endothelium-intact vessels) had no effect. In calcium-free solution, both the EM extract and phenanthrene inhibited extracellular Ca2+-induced contraction in high KCl and phenylephrine (PE) pre-contracted rings. They also inhibited the intracellular Ca2+ release sensitive to PE. The acute infusion of EM extract (20 and 70 mg/kg) induced an immediate and transient dose-dependent hypotensive effect.Conclusion: The ethanolic extract of EM tubers and its main active compound, 1-(4′-hydroxybenzyl)-4,8-dimethoxyphenanthrene-2,7-diol (phenanthrene) induced vasorelaxant effects on rat resistance vessels, through pleiotropic effects including endothelium-dependent effects (NOS activation, enhanced EDH production) and endothelium-independent effects (opening of KCa channels, inhibition of Ca2+ channels, inhibition of intracellular Ca2+ release and PDE inhibition).

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Section: Introductionmentioning

confidence: 99%

Vasorelaxant and Hypotensive Effects of an Ethanolic Extract of Eulophia macrobulbon and Its Main Compound 1-(4′-Hydroxybenzyl)-4,8-Dimethoxyphenanthrene-2,7-Diol

et al. 2018

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“…Tuberous terrestrial orchids have long been used as medicine and dietary supplements in different parts of the world (Bulpitt 2005;Bulpitt et al 2007;Chinsamy et al 2011;Hossain 2011). In the eastern Mediterranean, Asia Minor and the Middle East, tubers of different orchid species are collected indiscriminately from the wild and are traded for production of Salep tuber powder (Kasparek & Grimm 1999;Ece Tamer et al 2006;Sandal Erzurumlu & Doran 2011;Ghorbani et al 2014a;Kreziou et al 2015).…”

Section: Introductionmentioning

confidence: 99%

DNA barcoding of tuberous Orchidoideae: a resource for identification of orchids used in Salep

Ghorbani

Gravendeel

Selliah

et al. 2016

Molecular Ecology Resources

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“…Inflorescence corymbose (several, 3-4cm), much shorter when compared to leaves. Flowers are clustered (8)(9)(10)(11)(12), fragrant, long-lasting, are densely arranged and approximately 1.2cm across. Petals and sepals subequal, yellow, barred with red.…”

Section: Plant Descriptionmentioning

confidence: 99%

A comprehensive review on ethnobotanical applications and pharmacological activities of Acampe praemorsa (Roxb.) Blatt. & McCann (Orchidaceae)

Vibha¹,

Hebbar²,

Mahalakshmi³

et al. 2019

J. Drug Delivery Ther.

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Orchidaceae is one of the two largest families in angiosperms. Orchids are popular owing to the most beautiful flowers they produce and due to their wide spread ethnobotanical importance. In this review, ethnobotanical uses and pharmacological activities of A. praemorsa is discussed by referring flora, journals, and search engines such as Google scholar, ScienceDirect and Pubmed. Ethnobotanical investigations have revealed the potential therapeutic roles of different parts of A. praemorsa. The orchid is used traditionally by for treating ailments such as stomachache, earache, backache, wounds, neuralgia, rheumatism, eye diseases, sciatica, cough and fracture. A. praemorsa is investigated for various pharmacological activities. Studies have revealed the potential of A. praemorsa to exhibit a range of bioactivities such as anticancer, antibacterial, antifungal, antioxidant and anti-inflammatory activities. In conclusion, A. praemorsa is an extensively used epiphytic orchid for medicinal purposes in several parts of the India and other countries. Major emphasis has to be given in order to conserve this medicinally important orchid species. A. praemorsa can be a promising candidate in terms of its pharmacological potential.

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The ethnobotany of South African medicinal orchids

Cited by 49 publications

References 12 publications

Vasorelaxant and Hypotensive Effects of an Ethanolic Extract of Eulophia macrobulbon and Its Main Compound 1-(4′-Hydroxybenzyl)-4,8-Dimethoxyphenanthrene-2,7-Diol

Vasorelaxant and Hypotensive Effects of an Ethanolic Extract of Eulophia macrobulbon and Its Main Compound 1-(4′-Hydroxybenzyl)-4,8-Dimethoxyphenanthrene-2,7-Diol

DNA barcoding of tuberous Orchidoideae: a resource for identification of orchids used in Salep

A comprehensive review on ethnobotanical applications and pharmacological activities of Acampe praemorsa (Roxb.) Blatt. & McCann (Orchidaceae)

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