The Evaluation of Saliva Flow Rate, pH, Buffer Capacity, Microbiological Content and Indice of Decayed, Missing and Filled Teeth in Behçet’s Patients

Erdem, Vildan; Yıldız, Mehmet; Erdem, Teoman

doi:10.5152/balkanmedj.2013.7932

Cited by 12 publications

(10 citation statements)

References 16 publications

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“…The flow rate of stimulated saliva was calculated in mL/min. The BC (pH) and bacterial count of stimulated saliva were analyzed by means of the Caries Risk Test (CRT ® ) Kit (CRT ® Buffer & CRT ® Bacteria Kits, Ivoclar Vivadent AG) (Erdem et al, 2013) as per manufacturer’s instructions (Figure 2).…”

Section: Study Population and Methodsmentioning

confidence: 99%

Factors Affecting High Caries Risk in Children With and Without Cleft Lip and/or Palate: A Cross-Sectional Study

Chaudhari

Kharbanda

Bamola

et al. 2020

The Cleft Palate Craniofacial Journal

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Objective: The aim of the study was to analyze the caries protective factors, salivary parameters, and microbial counts in high caries risk children with cleft lip and/or palate (CL/P). Design: This was a cross-sectional study. Setting: This study was conducted in a tertiary health care teaching hospital in New Delhi, India. Participants: The study was conducted in 40 children, 20 with CL/P and 20 without aged between 5 and 12 years. Methods: Children with 2 or more caries lesions in both groups were included in this study. Demographic details, dental caries of affected teeth (World Health Organization criteria for Decayed Missing Filled Teeth [WHO-DMFT] and International Caries Detection and Assessment System [ICDAS II]), caries protective factors, salivary parameters, and microbial counts were recorded by one calibrated investigator. Main Outcome Measures: Caries protective factors, salivary parameters, and microbial profile. Results: The Chi-square (χ2) test and Pearson correlation were used for statistical analysis. All the children participating in the study brushed their teeth only once in a day and consumed sweets more than twice a day. None of the children had ever received fluoride varnish. Resting saliva had a low buffering capacity in 80% of children with CL/P and 95% of children without CL/P. Microbial assessment of stimulated saliva showed that with the increases in the numbers (DMFT scores ≥4) and severity (ICDAS codes from 1-2 to 5-6) of caries lesions, both Streptococci and Lactobacilli counts were ≥105 colony-forming units/mL of saliva in the both groups. Conclusions: Children with CL/P showed limited access to caries protective measures and low buffering capacity in resting saliva, along with elevated levels of salivary Streptococci and Lactobacilli in stimulated saliva.

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Section: Study Population and Methodsmentioning

confidence: 99%

Factors Affecting High Caries Risk in Children With and Without Cleft Lip and/or Palate: A Cross-Sectional Study

Chaudhari

Kharbanda

Bamola

et al. 2020

The Cleft Palate Craniofacial Journal

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“…The volume available for dissolution, or flow rate, should reflect physiological conditions since this affects the concentration gradient of solvated API molecules and saturation of the bulk fluid. Salivary flow rate has been investigated; however, most groups investigated either US [24] or SS [39]. Since inter-individual variation is so vast in these studies, flow rate should be considered for US and SS in the same individual to allow accurate comparison of stimulation states.…”

Section: Introductionmentioning

confidence: 99%

Characterisation of human saliva as a platform for oral dissolution medium development

Gittings

Turnbull

Henry

et al. 2015

European Journal of Pharmaceutics and Biopharmaceutics

134

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Human saliva is a biological fluid of great importance in the field of dissolution testing. However, until now, no consensus has been reached on its key characteristics relevant to dissolution testing. As a result, it is difficult to select or develop an in vitro dissolution medium to best represent human saliva. In this study, the pH, buffer capacity, surface tension, viscosity and flow rate of both unstimulated (US) and stimulated (SS) human saliva were investigated in order to provide a platform of reference for future dissolution studies using simulated salivary fluids. Age and gender related differences in a sample size of 30 participants for each parameter were investigated. Significant differences were established between US and SS for all characteristics except surface tension. Therefore, the requirement for using two simulated salivary fluids should be considered when developing an oral dissolution model.

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“…15 Brozovic in 2001 found that salivary flow rates did not differ significantly between acute RAU cases (either minor or major), during remission period and controls. 16 However no statistically significant differences were found between flow rate in active lesion and acquiescence. Similar flow rates were measured in patients with RAU in comparison to individuals with no prior history of such lesions.…”

Section: Discussionmentioning

confidence: 86%

“…24 In contrast, de Oliveira conducted a study and did not find any significant difference in salivary flow mean values between genders. 16 Quantitative changes in saliva did not seem to play a role in the course of minor recurrent apthous ulcer. However, severe cases of minor recurrent apthous ulcer, which are characterized by the presence of more than two ulcers in a single attack and a very frequent recurrence, may be accompanied by higher saliva production which may represent a reactive response towards the active presence of recurrent apthous ulcer in the mouth.…”

Section: Discussionmentioning

confidence: 91%

“…It was demonstrated there was high correlation between weight and volume of unstimulated whole saliva, however volume measures were found less reliable. 16 A sample of 4ml mixed whole unstimulated saliva was dispensed in a sterilized plane tube and its pH was determined using the pH meter (Laqua, Horiba, PH 1100). Table 3: Comparison of salivary pH between the case and control groups in accordance with gender and age group…”

Section: Methodsmentioning

confidence: 99%

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Evaluation of the Salivary Flow Rate and pH in Patients with Recurrent Oral Ulcers

Al-Ahmad¹,

Ezzat²,

Sukmasari³

et al. 2020

imjm

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Introductions: Recurrent oral ulcers primarily effect mucosal surfaces and are among the most common chronic inflammatory diseases. Numerous studies to find the aetiopathogenesis have been conducted however the cause still remains unclear. Saliva is of utmostimportance for oral health maintenance. In current study, saliva was used as a diagnostic tool for comparison of salivary flow rate and pH in patients suffering from recurrent oral ulcers and control group. Materials and Methods: Saliva samples taken from 20 recurrent aphthous ulcer patients and 20 control (healthy) patients using a convient sampling method. Drooling method was used to collect unstimulated whole saliva sample. Pre-weighted specimen bottles were used and then weighed after sample collection on a graduated scale where as chair-side pH meter was used to determine the salivary pH. Independent t-test and Pearson’s correlation were performed. A p-value of less than 0.05 was considered statistically significance. Results: Positive correlation was found between the flow rate and pH in recurrent oral ulcer patients. Patients with recurrent oral ulcers had higher flow rate and pH compared to the control group. These effects were exaggerated in female patients with ulcers. Conclusions: Disturbances in salivary flow rate and pH were not significantly associated with recurrent oral ulcers.

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The Evaluation of Saliva Flow Rate, pH, Buffer Capacity, Microbiological Content and Indice of Decayed, Missing and Filled Teeth in Behçet’s Patients

Cited by 12 publications

References 16 publications

Factors Affecting High Caries Risk in Children With and Without Cleft Lip and/or Palate: A Cross-Sectional Study

Factors Affecting High Caries Risk in Children With and Without Cleft Lip and/or Palate: A Cross-Sectional Study

Characterisation of human saliva as a platform for oral dissolution medium development

Evaluation of the Salivary Flow Rate and pH in Patients with Recurrent Oral Ulcers

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