The Frequency of Serous Macular Detachment in Diabetic Macular Edema

Yaya, Onur; Taş, İnan; Ayrancioğlu, Bedriye Nur; Önder, Ayşe Feyza

doi:10.4274/tjo.57805

Cited by 1 publication

(1 citation statement)

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“…In OCT studies of patients with DME, the prevalence of SD has been found to range from 11.4% to 51.9%. 8 , 9 , 10 , 11 , 12 In the present study, the most common OCT finding observed in patients was SD, which was present in approximately half of the patients. This result is consistent with the literature, as the results of more recent studies demonstrate a higher prevalence of SD compared to earlier studies.…”

Section: Discussionsupporting

confidence: 52%

Relationship Between Final Visual Acuity and Optical Coherence Tomography Findings in Patients with Diabetic Macular Edema Undergoing Anti-VEGF Therapy

Eraslan¹,

Yıldırım

Dursun

et al. 2020

tjo

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Objectives: To identify the prevalence of findings in optical coherence tomography (OCT) sections before intravitreal anti-VEGF treatment in patients with diabetic macular edema (DME), and to evaluate the relationship between these findings and final visual acuity and number of injections. Materials and Methods: This retrospective study included 296 eyes of 191 patients (104 male, 87 female) who started intravitreal ranibizumab treatment after being diagnosed with DME in the retina unit between January 2013 and April 2017 were included the study. Spectral domain OCT findings at the time of presentation such as presence of serous macular detachment (SD), vitreomacular traction (VMT), and epiretinal membrane (ERM) were recorded. In addition, the regularity of the ellipsoid zone (EZ) and inner retinal layers was also studied. Results: The mean central retinal thickness measured in SD-OCT was 449±81 μm before treatment and 350±96 μm after treatment (p<0.001). SD was detected in 155 eyes (52.4%), ERM in 67 eyes (22.6%), and VMT in 9 eyes (3%). Thirty eyes (10.1%) had disorganization of the retinal inner layers (DRIL) and 54 eyes (18.2%) had EZ deterioration. The presence of ERM, EZ irregularity, and DRIL were associated with significantly lower final visual acuity (p<0.0001), while there was no relationship between pre-treatment SD and final visual acuity (p=0.11). Injection number was higher in eyes with SD and ERM compared to those without, but this difference was statistically significant only in the presence of SD (p=0.01 and p=0.59, respectively). There was no difference in injection number according to EZ irregularity or presence of DRIL. Conclusion: The coexistence of SD with DME was associated with increased need for treatment but not with final visual acuity. EZ irregularities, DRIL, and ERM are findings that negatively affect visual acuity.

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