The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice

Pourgholami, Mohammad H.; Majzoob, Sayeh; Javadi, Mohammad Ali; Kamalinejad, Mohammad; Fanaee, G.H.R; Sayyah, Mohammad

doi:10.1016/s0378-8741(98)00161-5

Cited by 102 publications

(59 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As a medical herb, anise has been used as digestive stimulant and anthelmintic (Cabuk et al, 2003), antimicrobial (Singh et al, 2002), expectorant, carminative and antispasmodic (Zepernicket al, 1984), antioxidants (Gulcin et al, 2003) hypocholesterolemic (Craig, 1999), anticonvulsant (Pourgholam et al ., 1999), anti-fungal (Soliman and Badea, 2002), antipyretic (Afifi et al, 1994) and antiepileptic (Janahmadi et al ., 2008), increased milk production in lactating women and relief gastrointestinal troubles from her nursing infants (Zargari, 1996), muscle relaxant effect (Albuquerque et al,1995) and laxative (Chicouri and Chicouri, 2000). Anise seed is registered by the European Council as natural source of feed flavor and in the USA as GRAS, i.e.…”

Section: Introductionmentioning

confidence: 99%

Behavior, Fear Response, Performance and Immune Response of Broiler Chicks Fed Graded Levels of Anise Seed as Alternative to Antibiotics

Ramadan¹

2017

AJVS

View full text Add to dashboard Cite

Key words:Anise, seed, antibiotic, behavior, performance, stress, fear, immune response.A total of two hundred twenty five day-old Cobb broiler chicks were distributed into five groups (15 birds/ group, three replicates for each treatment). The dietary treatments were designed to fed the chicks of basal diet without supplementation (control), basal diet supplemented with 0.5, 0.75 and 1gm/kg anise seed, and basal diet supplemented with 10g/kg zinc bacitracin (anti-biotic group). Behavioral observation was carried out twice daily (7:00-11:30 am and 13:00-17:30 pm) two days a week for 6 consecutive weeks. Body weight (BW) and feed intake per pen were measured weekly from which body weight gain (BWG) and feed conversion ratio (FCR) were measured. Immune response against NDV was determined at 33 th day of age. At the end of experiment, fear responses, differential leucocyte count, Hb concentration, PCV, and some carcass traits were assayed. Dead birds from each treatment were recorded. The obtained results showed that higher proportion of birds supplemented with anise 0.5, 0.75 and 1.0 gm/kg were engaged in more feeding behavior compared to control one. Birds supplemented with anise seed and antibiotics were engaged in significantly more resting behavior compared to birds in control group. Untreated control birds exhibited significantly higher preening behavior and lower wing stretching and/or wing flapping and dust bathing behaviors compared to anise seed fed groups.At the 43 th day of age birds supplemented with 0.5, 0.75 and 1.0 gm/kg anise seed had significantly higher BW, BWG, and better FCR and had higher carcass percentage compared to birds in control group, but not significantly differed from birds in antibiotic group. Mortality rate was not differed among different treatments. Percent of live weight of bursa and Hb content were significantly higher in anise seed supplemented groups compared to control and anti-biotic groups. Chicks fed basal unsupplemented diet were more fearful in tonnic immobility test and were more stressed and had a significant increase in heterophil / lymphocyte ratio when compared with those in all supplemented diet groups. In contrast, dietary supplementation had no significant effect on antibody titer against NDV.In conclusion, dietary supplementation of broiler chicks with anise 0.5, 0.75 and 1.0 gm/kg improved feeding and comfort behaviors, improved productive performance and bird's welfare (reduced fear and stress) with no effect on immune response. Anise seed could be used as natural alternatives to feed antibiotics in broilers feed.

show abstract

Section: Introductionmentioning

confidence: 99%

Behavior, Fear Response, Performance and Immune Response of Broiler Chicks Fed Graded Levels of Anise Seed as Alternative to Antibiotics

Ramadan¹

2017

AJVS

View full text Add to dashboard Cite

show abstract

“…Additionally, anise is reported to possess anticonvulsant (Pourgholam et al, 1999), antiepileptic (Janahmadi et al, 2008) and muscle relaxant (Albuquerque et al, 1995) properties. Some studies have been conducted to evaluate the use of anise seed or oil in poultry nutrition, especially to replace antibiotics as growth promoters (Ciftci et al, 2005;Soltan et al, 2008;Al-Beitawi et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Use of anise seed and/or α-tocopheryl acetate in laying Japanese quail diets

Christaki¹,

Bonos²,

Florou-Paneri³

2011

SA J. An. Sci.

View full text Add to dashboard Cite

An experiment was conducted to investigate the possible use of anise (Pimpinella anisum) and/or α-tocopheryl acetate as dietary supplements on the performance and some egg quality characteristics of laying Japanese quail. One hundred and eight Coturnix japonica quail (72 females and 36 males), 149 days old, were randomly allocated to four equal groups with three subgroups of nine birds each (six females and three males). A commercial laying diet was fed to the control group (Group A). The remaining three groups received the same diet supplemented with anise seed at 10 g/kg (Group B) or 20 g/kg (Group C), or additional 600 mg α-tocopheryl acetate/kg (Group D). The birds were given feed and water ad libitum for a period of 29 days, while being kept under commercial conditions. During the experiment, egg production, feed consumption and mortality were recorded daily. Also, at the end of experiment, egg weight, egg yolk, albumen and shell weight percentages, egg yolk colour (using the L*a*b* colour space), blood serum total cholesterol and triglycerides concentrations were determined. Neither the supplementation of anise nor that of α-tocopheryl had any effect on the performance of the birds or the quality of their eggs, except for a significant change of the colour of the egg yolk. Cholesterol concentration in the serum tended to decrease with the addition of anise to the diet. ________________________________________________________________________________

show abstract

“…[31]  Pimpinella anisum: The essential oil of fruits of the plant was found to be anticonvulsant as it suppressed the tonic convulsions in mice induced by PTZ and MES treatment. [32] Zeba et al [33]  Solanum nigrum: Aqueous extract of leaf of Mako (Solanum nigrum) was found to offer protection against electrically, PTZ and picrotoxin induced seizure. 60mg/kg gave 75% protection against picrotoxin induced seizure in rats and also provided complete protection against mortality.…”

Section: World Journal Of Pharmaceuticalmentioning

confidence: 99%

A REVIEW: ANIMAL MODELS FOR SCREENING ANTIEPILEPTIC DRUGS & IMPORTANT UNANI ANTICONVULSANT DRUGS

Afrin¹

2017

WJPR

View full text Add to dashboard Cite

show abstract

The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice

Cited by 102 publications

References 5 publications

Behavior, Fear Response, Performance and Immune Response of Broiler Chicks Fed Graded Levels of Anise Seed as Alternative to Antibiotics

Behavior, Fear Response, Performance and Immune Response of Broiler Chicks Fed Graded Levels of Anise Seed as Alternative to Antibiotics

Use of anise seed and/or α-tocopheryl acetate in laying Japanese quail diets

A REVIEW: ANIMAL MODELS FOR SCREENING ANTIEPILEPTIC DRUGS & IMPORTANT UNANI ANTICONVULSANT DRUGS

Contact Info

Product

Resources

About