2016
DOI: 10.1038/nature17993
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The genetic history of Ice Age Europe

Abstract: Modern humans arrived in Europe ~45,000 years ago, but little is known about their genetic composition before the start of farming ~8,500 years ago. We analyze genome-wide data from 51 Eurasians from ~45,000-7,000 years ago. Over this time, the proportion of Neanderthal DNA decreased from 3–6% to around 2%, consistent with natural selection against Neanderthal variants in modern humans. Whereas the earliest modern humans in Europe did not contribute substantially to present-day Europeans, all individuals betwe… Show more

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Cited by 822 publications
(1,031 citation statements)
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References 55 publications
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“…In the near future, we expect that this approach will be superseded by target-enrichment methods coupled with high-throughput sequencing. In horses, such approaches have been applied to only a limited number of loci (Vilstrup et al 2013;Sarkissian et al 2015), but recent procedures enable genotyping millions of loci genome wide (Fu et al 2016), and even entire chromosomes (Fu et al 2013) and genomes (Carpenter et al 2013). This will likely facilitate the identification of the whole series of genetic modifications that have accompanied the recent evolutionary history of this family, domestication and extinction processes included.…”
Section: Predomestication Timesmentioning
confidence: 99%
“…In the near future, we expect that this approach will be superseded by target-enrichment methods coupled with high-throughput sequencing. In horses, such approaches have been applied to only a limited number of loci (Vilstrup et al 2013;Sarkissian et al 2015), but recent procedures enable genotyping millions of loci genome wide (Fu et al 2016), and even entire chromosomes (Fu et al 2013) and genomes (Carpenter et al 2013). This will likely facilitate the identification of the whole series of genetic modifications that have accompanied the recent evolutionary history of this family, domestication and extinction processes included.…”
Section: Predomestication Timesmentioning
confidence: 99%
“…of about 30,000 years ago and later (Fu et al, 2016). In those skeletons (in the Czech Republic, Rumania, Russia, Germany, Belgium, Spain, Italy) there were discovered the Y Chromosome haplogroups BT, CT, C, F, I and the haplogroups HIJK and IJK, which derived from the haplogroup F and which are ancestors of haplogroup I.…”
Section: ) Another Important Information Was Derived From the Europementioning
confidence: 99%
“…Price et al 2004, Evans et al 2006, Boel 2011; see also for the Corded Ware Sjögren et al 2016 who report possible female exogamy, although the sex ratio of local / non-local individuals does not present any statistical significance). The period is indeed characterised by high frequency of human mobility, in some exceptional cases over long distance (Fitzpatrick 2011) but which concerns in equal measure men and women, ruling out the presence of of consistent postmarital relocation rules.…”
Section: Fitness Marriage Demographymentioning
confidence: 99%