The guided-mode resonance biosensor: principles, technology, and implementation

Magnusson, Robert; Lee, Kyu J.; Hemmati, Hafez; Ko, Yeong Hwan; Wenner, Brett R.; Allen, Jeffery; Allen, Monica; Gimlin, Susanne; Weidanz, Debra Wawro

doi:10.1117/12.2288795

Cited by 13 publications

(8 citation statements)

References 63 publications

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“…. and transmittance T 0 , T 1 , T 2 ..) by interacting with the diffraction structure, resulting in a very narrow reflectance or transmittance resonant bandwidth [55][56][57][58][59]. The resonant peak is highly sensitive to the changes in surrounding refractive index, which is used in determining target analytes and the corresponding concentrations [58].…”

Section: Guided Mode Resonance-based Biosensormentioning

confidence: 99%

Review of Integrated Optical Biosensors for Point-of-Care Applications

et al. 2020

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This article reviews optical biosensors and their integration with microfluidic channels. The integrated biosensors have the advantages of higher accuracy and sensitivity because they can simultaneously monitor two or more parameters. They can further incorporate many functionalities such as electrical control and signal readout monolithically in a single semiconductor chip, making them ideal candidates for point-of-care testing. In this article, we discuss the applications by specifically looking into point-of-care testing (POCT) using integrated optical sensors. The requirement and future perspective of integrated optical biosensors for POC is addressed.

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Section: Guided Mode Resonance-based Biosensormentioning

confidence: 99%

Review of Integrated Optical Biosensors for Point-of-Care Applications

et al. 2020

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“…In 2000, a new type of GMR device integrating a waveguide grating with a subwavelength period on the endface of an optical fiber was proposed by Wawro et al [7] . In addition, the advantages of no fluorescent labeling, easy integration, and real-time detection have made GMR-based grating sensors widely used in biomedical sensing [8,9] . In 2005, Magnusson et al described the characteristics of GMR and demonstrated their utility in biosensors [10] .…”

Section: Introductionmentioning

confidence: 99%

High performance optical sensor based on double compound symmetric gratings

Shi

Liu

et al. 2022

Chin. Opt. Lett.

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A high performance optical sensor based on a double compound symmetric gratings (DCSGs) structure is designed. The reflection spectrum of the DCSG is investigated by utilizing a method that combines a theoretical model with the eigenmode information of the grating structure. The theoretical results, which are observed to agree well with those acquired by rigorous coupled-wave analysis, show that the linewidth of the reflection spectrum decreases upon the increasing distance between the grating strips. This research work will lay a foundation for studying high performance integrated optical sensors in miniature nanostructures.

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“…Among the mentioned optical sensors, − GMR is of interest because of the flexibility of the structure design. It can be constructed with different optical materials, including metal oxides, which are normally used in VOC sensing.…”

Section: Introductionmentioning

confidence: 99%

“…This resonance spectrum can be shifted according to the changes in the refractive index on the device’s surface as well as inside the film layers. As a result, GMR devices have been intensively utilized for sensing applications, especially in label-free biosensors. , Only few studies have been reported for VOC or gas-sensing applications. − Lately, GMR integrated on a fiber tip has been demonstrated for the detection of gaseous ethylene and methanol, where GO is coated on the sensor to enhance molecular adsorption . A copper(I) complex-1 coated on the GMR fiber sensor was shown to produce a highly selective ethylene sensor for crop/fruit diagnostic .…”

Section: Introductionmentioning

confidence: 99%

A Nanocolumnar Tantalum Oxide-Guided Mode Resonance Sensor for Volatile Organic Compounds

Srisuai

Chananonnawathorn

Seeleang

et al. 2021

ACS Appl. Nano Mater.

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In this work, a nanocolumnar tantalum oxide waveguide is introduced in a guided-mode resonance-based sensor for volatile organic compound detection. The presence of a nanocolumnar structure where optical resonance is localized allows for molecular diffusion and adsorption and hence the enhancement of the sensor’s sensitivity. Here, the nanocolumnar tantalum oxide film is fabricated using a pulsed direct current reactive magnetron sputtering system at low kinetic energy deposition. By optimizing the operation pressure, both the size and density of the nanocolumnar film can be controlled. The results show that the tantalum oxide film deposited at a higher pressure (30 mTorr) forms a more discrete nanocolumnar structure (refractive index of 1.93 and 20.7% porosity). As a result, the sensor’s sensitivity is remarkably increased up to 15-fold in comparison to the deposition at a lower pressure (10 mTorr, higher refractive index, n = 2.1, and 6.4% porosity). The sensor exhibits good stability and reusability over 25 measurements of isopropanol vapor within a duration of 60 days with 6.4% coefficient of variance at a lower concentration (5%). The selectivity experiment shows good potential of using the proposed sensor for toluene and formaldehyde detection.

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The guided-mode resonance biosensor: principles, technology, and implementation

Cited by 13 publications

References 63 publications

Review of Integrated Optical Biosensors for Point-of-Care Applications

Review of Integrated Optical Biosensors for Point-of-Care Applications

High performance optical sensor based on double compound symmetric gratings

A Nanocolumnar Tantalum Oxide-Guided Mode Resonance Sensor for Volatile Organic Compounds

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