Millions of hectares of agricultural land could be released from human pressure within the next decades in Europe. Rewilding presents a great opportunity to restore the abandoned landscapes, along with the biodiversity and the supply of those ecosystem services that were until now restricted to the remaining few wild areas of the continent. As a result, rewilding is in a dire need of a policy framework in the European Union, to promote its implementation as a land management option, to evaluate its outcomes, and to share knowledge and good practices among stakeholders. In this chapter, we review the history of conservation policies and protected areas in the EU, the implementation of the Natura 2000 Network being one of the major milestones. We also discuss the role of conservation in sectoral activities such as agriculture. We present the growing importance given to wilderness areas and the inclusion of wilderness management into European policies. We then evaluate the contribution of wilderness and rewilding to the achievement of global and EU targets. Finally, recommendations are made to efficiently and adequately include rewilding into the European framework of conservation policies.