The Honey, The Poison, The Weapon

Gunduz, Abdülkadir; Türedi, Süleyman; Öksüz, Hikmet

doi:10.1016/j.wem.2011.01.006

Cited by 15 publications

(19 citation statements)

References 12 publications

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“…This fact highlights the importance of selecting an appropriate variety of honey, which means that a previous screening is necessary in order not only to quantify but also to determine profiles of bioactive substances [19,30]. In addition, it is necessary to consider that, although minor, there is a possibility that honey might induce negative effects, either by ingestion [122,123] or by topical use, mainly related to the presence of Clostridium botulinum spores, which have occasionally been found in honey [19,124,125]; however, to date, no cases of wound infection due to C. botulinum spores related to the use of non-irradiated honey were reported. Moreover, honey for medical uses must be free of any form of contamination, such as herbicides, pesticides, heavy metals, and spores-to meet all these criteria, honey must be collected in organic regions, as well as following strict quality, processing, and storage standards and regulations, in order to ensure its safety [108].…”

Section: Limitations Of the Use Of Honey In Therapymentioning

confidence: 99%

Honey: Another Alternative in the Fight against Antibiotic-Resistant Bacteria?

et al. 2020

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Antibacterial resistance has become a challenging situation worldwide. The increasing emergence of multidrug-resistant pathogens stresses the need for developing alternative or complementary antimicrobial strategies, which has led the scientific community to study substances, formulas or active ingredients used before the antibiotic era. Honey has been traditionally used not only as a food, but also with therapeutic purposes, especially for the topical treatment of chronic-infected wounds. The intrinsic characteristics and the complex composition of honey, in which different substances with antimicrobial properties are included, make it an antimicrobial agent with multiple and different target sites in the fight against bacteria. This, together with the difficulty to develop honey-resistance, indicates that it could become an effective alternative in the treatment of antibiotic-resistant bacteria, against which honey has already shown to be effective. Despite all of these assets, honey possesses some limitations, and has to fulfill a number of requirements in order to be used for medical purposes.

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Section: Limitations Of the Use Of Honey In Therapymentioning

confidence: 99%

Honey: Another Alternative in the Fight against Antibiotic-Resistant Bacteria?

et al. 2020

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“…Mad honey intoxication has been reported from different countries around the globe, and the origin can be traced back to the Black Sea region of Turkey or Nepal. 45, [67][68][69] Table 2 shows recently (2010 onward) reported cases of mad honey intoxication/poisoning, evidencing that mad honey is still widely consumed.…”

Section: Mad Honeymentioning

confidence: 99%

Mad honey: uses, intoxicating/poisoning effects, diagnosis, and treatment

et al. 2018

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“…Mad honey is known due to intoxications encountered during its use as both a therapeutic product and as a normal foodstuff for hundreds of years. (1). The mechanism involved in the formation of mad honey largely involves the grayanotoxin (GTX) contained in the nectars of the plants Rhododendron ponticum and Rhododendron luteum being mixed into honey by bees (2).…”

Section: Introductionmentioning

confidence: 99%

The effect of mad honey on testosterone levels of male rats

Tatlı¹,

Karaca²,

Turkmen³

et al. 2017

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OBJECTIVE: We aimed to investigate the effect of mad honey on sexual performance. BACKGROUND: In traditional medicine in Turkey, mad honey is used to improve appetite, to heighten mental alertness, to reduce joint pain, to eliminate gastrointestinal system pains and to increase sexual performance. METHODS: In this experimental animal study eighteen Sprague Dawley male rats were randomized into three groups, a control group, a normal honey group and a mad honey group. Rats in the treatment groups were given a daily dose of 80 mg/kg normal honey or mad honey throughout the 30-day study period. Total testosterone, free testosterone, FSH, LH, estradiol, and progesterone levels were subsequently investigated from blood sera on day 30. RESULTS: Comparison of blood total testosterone levels among the groups revealed signifi cantly higher levels in the mad honey group compared to the normal honey and control groups (p = 0.006, p = 0.00). Free testosterone levels were also signifi cantly higher in the mad honey group than in the normal honey and control groups (p = 0.023, p = 0.01). No statistically signifi cant differences were determined for other hormonal measurements. CONCLUSIONS: This study revealed a signifi cant increase in both total and free testosterone levels in mad--honey group (Tab. 1, Fig. 2

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The Honey, The Poison, The Weapon

Cited by 15 publications

References 12 publications

Honey: Another Alternative in the Fight against Antibiotic-Resistant Bacteria?

Honey: Another Alternative in the Fight against Antibiotic-Resistant Bacteria?

Mad honey: uses, intoxicating/poisoning effects, diagnosis, and treatment

The effect of mad honey on testosterone levels of male rats

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