The ICD-10 Charlson Comorbidity Index predicted mortality but not resource utilization following hip fracture

Toson, Barbara; Harvey, Lara; Close, Jacqueline C.T.

doi:10.1016/j.jclinepi.2014.09.017

Cited by 83 publications

(74 citation statements)

References 29 publications

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“…We used the CCI as a well-accepted comorbidity burden index for adjusting for concomitant diseases [22, 23, 44, 45, 52, 53]. We chose the CCI because of its adaptability to large population databases using diagnostic codes from the ICD-10 [44].…”

Section: Discussionmentioning

confidence: 99%

“…it equates the entities. Models incorporating comorbidities as individual variables perform better in predicting mortality than the weighted index [22]. The CCI ignores most of the disorders known to cause secondary osteoporosis [54], and it does not include hyperthyroidism or Parkinson’s disease which are known to increase the propensity to falls [47].…”

Section: Discussionmentioning

confidence: 99%

“…We also updated disease weighting to reflect advances in chronic disease management and treatment outcomes since the introduction of the original Charlson index in 1984 [21]. The updated Charlson index has demonstrated comparable predictive utility for mortality using ICD-10 coded administrative data [21] and has been validated among hip fracture patients [22]. …”

Section: Methodsmentioning

confidence: 99%

“…Comorbidities were defined as secondary or other diagnoses coded at the index hip fracture claim and/or diagnoses of any type on hospital or outpatient health care claims during the year preceding the index date [22, 23]. We applied a restriction to outpatient claims, such that a comorbid condition could be flagged during the preceding period only if it appeared two or more times at least 7 days apart [7, 23].…”

Section: Methodsmentioning

confidence: 99%

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The impact of hip fracture on mortality in Estonia: a retrospective population-based cohort study

Jürisson

Raag

Kallikorm

et al. 2017

BMC Musculoskelet Disord

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BackgroundEstimates of hip fracture mortality in Eastern Europe are scarce. We aimed to estimate the magnitude and duration of excess mortality after hip fracture in Estonia.MethodsRetrospective, population-based 10-year study of persons aged ≥50 in two cohorts: with hip fracture and an age- and sex-matched (in a 1:4 ratio) random sample from the national health insurance fund database for comparison. Cumulative risks, excess risks and relative risks of death were estimated using Poisson regression with 95% bootstrap confidence intervals (CI). Risks were adjusted for age and Charlson comorbidity index.ResultsWe identified 8298 (2383 men, 5915 women) incident hip fracture patients from 2005 to 2013 and 33,191 (9531 men, 23,660 women) individuals for the reference group. 5552 (1564 men, 3988 women) cases and 14,037 (3514 men, 10,523 women) reference individuals died during the 10-year follow-up period. Among hip fracture patients we observed a pronounced and durable excess risk of death that was highest within 3–6 months after fracture and persisted for the full 10-year follow-up period. After adjustment for age and Charlson index, hip fracture was associated with a 21.1% (95% CI 20.0–22.5%) 10-year cumulative excess risk of death (RR 1.37, 95% CI 1.35–1.40). We found a high immediate excess risk of death in older age groups (≥80 years) and gradually accumulating excess risk in younger age groups (50–79 years). The excess risk was more pronounced among men than women.ConclusionsBy the end of the 10-year follow-up, 1 in 4 deaths in the hip fracture group was attributable to the hip fracture. The results indicate a high attributable impact of hip fracture as an independent risk factor for death.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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The impact of hip fracture on mortality in Estonia: a retrospective population-based cohort study

Jürisson

Raag

Kallikorm

et al. 2017

BMC Musculoskelet Disord

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“…Determination of the mortality risk of hip fractures in elderly patients should be evaluated as an important prerequisite but when orthopaedics and traumatology literature is examined, it can be seen that there is limited number of studies on this issue, and an adequate and also effective method has not been developed yet 8,9,12,[17][18][19] . Within this context, the current study is the first in orthopaedics and traumatology literature to show that the ACE-27 scoring system could be of use in the determination of mortality risk at 1-year following hip fractures in elderly patients who have a relatively high mortality rate.…”

Section: Discussionmentioning

confidence: 99%

Is ACE-27 a reliable method for predicting mortality of hip fractures treated with hemiarthroplasty in the elderly?

Tahta¹,

Bulut²,

Öztürk³

et al. 2016

MMJ

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Mortality Among Hospitalized Individuals With Systemic Lupus Erythematosus in the US Between 2006 and 2016

Anastasiou

Trupin

Glidden

et al. 2021

Arthritis Care & Research

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Objective To evaluate time trends in mortality for hospitalized adults with systemic lupus erythematosus (SLE) compared to the general hospitalized population (GHP), and to identify factors associated with increased risk of death among hospitalized SLE patients. Methods We used the National (Nationwide) Inpatient Sample to estimate all‐cause mortality for adults discharged from community hospitals in the US between 2006 and 2016. Poisson regression models were used to estimate the risk of in‐hospital death among all patients, including demographic characteristics, socioeconomic factors, comorbidity score, hospital region, SLE diagnosis, and race/ethnicity as covariates. Results Among 340,467,049 hospitalizations analyzed, 1,903,279 had a discharge diagnosis of SLE. In adjusted analysis, the risk of inpatient death decreased among hospitalizations for patients with SLE from 2.2% to 1.5% (P < 0.001) between 2006 and 2016. All of the decrease in SLE mortality occurred between 2006 and 2008; after 2008, mortality stabilized at a rate statistically similar to the GHP. Hospitalizations for Black, Hispanic, and Asian/Pacific Islander patients with SLE were more likely to end in death compared to hospitalizations for either White patients with SLE or individuals of the same non‐White race/ethnicity without SLE. Conclusion In the largest study of in‐hospital SLE mortality published to date, we found significant improvements in mortality for hospitalized patients with SLE in the US from 2006 until 2008, after which mortality stabilized at a level similar to that of the GHP. Our results also demonstrate a persistently high mortality burden among Black and Hispanic patients with SLE in the US and contribute new data revealing high mortality among Asian/Pacific Islander patients with SLE.

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The ICD-10 Charlson Comorbidity Index predicted mortality but not resource utilization following hip fracture

Cited by 83 publications

References 29 publications

The impact of hip fracture on mortality in Estonia: a retrospective population-based cohort study

The impact of hip fracture on mortality in Estonia: a retrospective population-based cohort study

Is ACE-27 a reliable method for predicting mortality of hip fractures treated with hemiarthroplasty in the elderly?

Mortality Among Hospitalized Individuals With Systemic Lupus Erythematosus in the US Between 2006 and 2016

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