The Impact of a Monensin Controlled-Release Capsule on Subclinical Ketosis in the Transition Dairy Cow

Green, B.L.; McBride, B.W.; Sandals, D.; Leslie, K.E.; Bagg, R.; Dick, P.

doi:10.3168/jds.s0022-0302(99)75240-9

Cited by 94 publications

(146 citation statements)

References 30 publications

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“…Rumen pH tended to be greater in animals consuming C-bm3 = no monensin, bm3 hybrid; C-DP = no monensin, dual-purpose control hybrid; M-bm3 = 300 mg/ d monensin, bm3 hybrid; M-DP = 300 mg/d monensin, control dual-purpose hybrid. monensin and is consistent with the observations of others (Green et al, 1999). Although ruminal lactate was not measured in the current study, elevations in rumen pH when animals are fed monensin are believed to occur because of the sensitivities of lactate-producing bacteria to this compound (Russell and Strobel, 1989).…”

Section: Rumen Ph Vfa and Ammoniasupporting

confidence: 80%

Evaluation of Nitrogen Utilization and the Effects of Monensin in Dairy Cows Fed Brown Midrib Corn Silage

Gehman

Kononoff

Mullins

et al. 2008

Journal of Dairy Science

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Twenty midlactation Holstein cows (4 ruminally fistulated) averaging 101 ± 34 d in milk and weighing 674 ± 77 kg were used to compare rations with brown midrib corn silage (bm3) to rations with dual-purpose control silage (DP) on N utilization and milk production. The effect of monensin in these rations was also examined. Animals were assigned to one of five 4 × 4 Latin squares with treatments arranged in a 2 × 2 factorial. Cows were fed 1 of 4 treatments during each of the four 28-d periods. Treatments were 1) 0 mg/d monensin and bm3 corn silage, 2) 0 mg/d monensin and DP corn silage, 3) 300 mg/d monensin and bm3 corn silage, and 4) 300 mg/d monensin and DP corn silage. In vitro 30-h neutral detergent fiber (NDF) digestibility was greater for bm3 corn silage (61.0 vs. 49.1 ± 0.62). Dry matter intake (DMI) tended to be greater for cows consuming bm3 corn silage (21.3 vs. 20.2 kg/d). Neither hybrid nor monensin affected milk production, fat, or protein (37.7 kg, 3.60%, or 3.04%). Monensin tended to increase rumen pH (5.89 vs. 5.79 ± 0.07) compared with the control treatment. In addition, bm3 corn silage resulted in a significant decrease in rumen pH (5.72 vs. 5.98 ± 0.07). Supplementing monensin had no effect on molar proportions of acetate, propionate, or butyrate. In contrast, an increase was observed in branched-chain volatile fatty acids. No treatment interactions were observed for rumen pH or molar proportion of propionate but monensin decreased the molar proportion of acetate and increased the molar proportion of butyrate when cattle consumed bm3 silage. Dry matter, N, and acid detergent fiber digestibility were lower for the bm3 ration, whereas NDF digestibility was not different between treatments. There was no effect of hybrid on Corresponding author: pkononoff2@unl.edu 288 microbial protein synthesis (1,140 g/d) as estimated by urinary concentration of purine derivatives. Cows consuming bm3 excreted more fecal N than cows consuming DP (38.2 vs. 34.4% N intake); however, based on spot sampling, estimated urinary and manure N were not different between treatments (35.8 and 71.9% N intake). Monensin had no effect on DMI, digestibility of any nutrients, or N metabolism, and there were no hybrid by monensin interactions. Rations including bm3 corn silage tended to increase DMI but did not affect production. The reduction in the digestibility of some nutrients when cows consumed bm3 may have been caused by increased DMI and possible increased digestion in the lower gut. This increase in DMI appeared to also have negatively affected N digestibility but not NDF digestibility. This resulted in a greater amount of N excreted in feces but did not affect total mass of manure N.

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Section: Rumen Ph Vfa and Ammoniasupporting

confidence: 80%

Evaluation of Nitrogen Utilization and the Effects of Monensin in Dairy Cows Fed Brown Midrib Corn Silage

Gehman

Kononoff

Mullins

et al. 2008

Journal of Dairy Science

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“…However, other studies have not shown milk fat depression following monensin administration (e.g., Lean et al, 1994;Duffield et al, 1999). The milk protein content of monensintreated cows was lower than for control cows, in agreement with Hayes et al (1996), Green et al (1999), and Phipps et al (2000), although other studies (e.g., Ramanzin et al, 1997;Benchaar et al, 2006) have not shown a protein response with monensin.…”

Section: Resultsmentioning

confidence: 54%

Long-Term Effects of Feeding Monensin on Methane Production in Lactating Dairy Cows

Odongo

Bagg

Vessie

et al. 2007

Journal of Dairy Science

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153

137

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The objective of this study was to determine the longterm effects of feeding monensin on methane (CH 4 ) production in lactating dairy cows. Twenty-four lactating Holstein dairy cows (1.46 ± 0.17 parity; 620 ± 5.9 kg of live weight; 92.5 ± 2.62 d in milk) housed in a tie-stall facility were used in the study. The study was conducted as paired comparisons in a completely randomized design with repeated measurements in a color-coded, double-blind experiment. The cows were paired by parity and days in milk and allocated to 1 of 2 treatments: 1) the regular milking cow total mixed ration (TMR) with a forage-to-concentrate ratio of 60:40 (control TMR; placebo premix) vs. a medicated TMR (monensin TMR; regular TMR + 24 mg of Rumensin Premix/kg of dry matter) fed ad libitum. The animals were fed and milked twice daily (feeding at 0830 and 1300 h; milking at 0500 and 1500 h) and CH 4 production was measured prior to introducing the treatments and monthly thereafter for 6 mo using an open-circuit indirect calorimetry system. Monensin reduced CH 4 production by 7% (expressed as grams per day) and by 9% (expressed as grams per kilogram of body weight), which were sustained for 6 mo (mean, 458.7 vs. 428.7 ± 7.75 g/d and 0.738 vs. 0.675 ± 0.0141, control vs. monensin, respectively). Monensin reduced milk fat percentage by 9% (3.90 vs. 3.53 ± 0.098%, control vs. monensin, respectively) and reduced milk protein by 4% (3.37 vs. 3.23 ± 0.031%, control vs. monensin, respectively). Monensin did not affect the dry matter intake or milk yield of the cows. These results suggest that medicating a 60:40 forage-to-concentrate TMR with 24 mg of Rumensin Premix/kg of dry matter is a viable strategy for reducing CH 4 production in lactating Holstein dairy cows.

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“…Na literatura, encontram-se trabalhos nos quais se obteve aumento da produção de leite em vacas sob suplementação com esse ionóforo (Hayes et al, 1996;Lean et al, 1996;Fellner, 1997;Beckett et al,1998;Sauer et al, 1998;Van Der Werf et al, 1998), enquanto em outros trabalhos (Baile et al, 1982;Dye et al, 1988;Sauer et al, 1989;Ramanzin et al, 1997;Phipps 1997;Green et al, 1999;Juchem et al, 2004), incluindo este, não houve aumento na produção de leite. Existem inúmeros fatores relacionados a esta diferença da ação da monensina na produção de leite, como raça, quantidade de concentrado oferecido e quantidade e duração da administração do ionóforo (Kennelly & Lien, 1997 Duffield et al (1999), a condição corporal dos animais também pode afetar essa resposta.…”

Section: Resultsunclassified

Efeitos da administração de monensina por meio de cápsulas de liberação controlada no desempenho de vacas Holandesas no início da lactação

Conti

Salles

Schalch³

2008

R. Bras. Zootec.

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RESUMO -Com o objetivo de estudar o efeito da monensina sobre a produção e composição de leite, a contagem de células somáticas, a condição corporal e os parâmetros sangüíneos e reprodutivos de vacas da raça Holandesa de alta produção no início de lactação, foram utilizadas 44 vacas com produção diária de 33,44 ± 4,93 litros de leite, em delineamento inteiramente casualizado, com dois tratamentos: um controle (C) e outro com cápsulas de liberação controlada de monensina com eficácia de 100 dias (300 mg/vaca/dia). A administração individual de monensina foi realizada 30 dias antes da data provável do parto. A monensina não alterou a produção, a composição do leite e a contagem de células somáticas do leite nem a condição corporal e a concentração de glicose e BHBA (beta-hidroxibutirato) no soro das vacas, no entanto, diminuiu a concentração de AGNE (ácidos graxos não-esterificados) no soro das vacas com 60 dias de lactação. O período de serviço e o número de serviços por concepção não diferiram entre os tratamentos, porém, a administração de monensina diminuiu o número de animais que apresentaram retenção de placenta e laminite. A administração de monensina para vacas Holandesas de alta produção no início de lactação não modifica a produção e a composição do leite, contudo, diminui a concentração de AGNE 60 dias após o parto e a incidência de laminite e retenção de placenta nas vacas no pós-parto.Palavras-chave: ácidos graxos não-esterificados, composição e produção do leite, glicose, ionóforo, parâmetros reprodutivos Effects of administration controlled released monensin capsules on performance of Holstein cows in the beginning of lactation ABSTRACT -The objective was to study the effect of the monensin on milk yield and milk composition, somatic cell count, body condition score, serum parameters and reproductive aspects high producing Holstein cows in early lactation. Fourty-four cows with daily milk yield of the 33.44 ± 4.93 liter of milk were assigned to a completely randomized design with two treatments: control (C) and other with controlled released monesin capsule with eficacy of 100 days (300 mg/cow/ day). The individual administration of the monensin capsule was made 30 day before the probable calving time. Monensin did not affect the milk yield and milk composition, somatic cell count, body condition score and glucose and BHBA (betahidroxibutirate) concentration in the cow blood serum. However, decreased concentration of NEFA (Non esterified fatty acid) in blood serum of cow with 60 days in milk. Service period and number of services per conception was not affected by treatments, however, the administration monensin decreased the number of the cows that showed retained placenta and laminitis. The administration monensin for high producing Holstein cows in early lactation did not change the milk production and composition. However, decrease the concentration of NEFA 60 days post calving and the incidence of laminitis and retained placenta in the post calving cows.Key Words: NEFA, glucose, ionosphor, milk...

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The Impact of a Monensin Controlled-Release Capsule on Subclinical Ketosis in the Transition Dairy Cow

Cited by 94 publications

References 30 publications

Evaluation of Nitrogen Utilization and the Effects of Monensin in Dairy Cows Fed Brown Midrib Corn Silage

Evaluation of Nitrogen Utilization and the Effects of Monensin in Dairy Cows Fed Brown Midrib Corn Silage

Long-Term Effects of Feeding Monensin on Methane Production in Lactating Dairy Cows

Efeitos da administração de monensina por meio de cápsulas de liberação controlada no desempenho de vacas Holandesas no início da lactação

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