Men and women farmers experience different impacts of climate variability and change (CVC). Research on the differentiated impacts of variability and change in rainfall on gender is limited in the study area. This study examined perceptions and experience of men and women farmers on the impacts of CVC, using climate data and farmers' perception from a gender perspective. It examined the effect of CVC on annual and seasonal rainfall, number of rain days, onset and cessation of rainfall; perceived impacts of CVC on annual and seasonal rainfall and compared the measured (meteorological) impacts with the perceived impacts across gender. Mixed methods of qualitative and quantitative data collection and participatory rural approaches were used. Household survey of 50% men and 50% women each were conducted in six farming communities. Data analysis involved the use of annual rainfall trends, Annual Rainfall Anomaly (ARA), Standardized Annual Rainfall Anomaly (SARA), regression analysis percentages and chi-square. Results reveal the occurrences of more dry years than wet years (ARA and SARA <0.00) in the three locations. There were wide variability and changes in inter-annual rainfall in Ogbaru (R
2
= 0.0003), Anambra East (R
2
= 0.0071) and Ayamelum (R
2
= 0.0014). Seasonal rainfall was unevenly distributed from 2007-2016. There were wide variations in dates of onset and cessation of rainy season (R
2
= 0.006) and number of rain days (R
2
= 0.009). Men and women responses revealed that there were statistically significant (p < 0.005) changes in the onset of rainy season, early cessation of annual rainfall; alteration of growing seasons; frequent flooding and frequent drought. Women felt more impact of food insecurity, water shortage and had more burden of migration due to changes in rainfall. This study concludes that respondents perceived and experienced impacts of CVC which varied across gender. Hence, it recommends the provision of sustainable water and irrigation system which should encourage women's participation in the construction, maintenance and management among others.