The quality of life is an integral indicator that includes the following indicators: the level of health of the population, education, employment, poverty, spending and consumption, life expectancy at birth, and so on. There are economic, social, ecological and climatic, political and cultural criteria for the quality of life. The problem of ensuring the proper level and quality of life of miners in mining regions is considered on the example of the Kemerovo region (Kuzbass). Unfavorable production factors in coal mining include meteorological conditions, pollution of the mine atmosphere with harmful gases, the release of coal dust during any technological processes, dust formation, lack of sunlight, noise and vibration, high risk of injury; difficult water supply and sanitation. These factors contribute to the formation of occupational diseases, which leads to a decrease in the quality of life. It is necessary to develop a set of measures to eliminate the identified problems: structural changes in the industry, the development of coal-technical, coal-chemical and energy-coal clusters, improving the consumer properties of coal products to expand sales markets, the formation of new professional standards and improving the system of training and advanced training of personnel, the introduction of unified systems of industrial and environmental safety.