The impact of obesity on fertility and sexual function in women of child bearing age

Deniz, Alparslan; Okuyucu, Muhammed

doi:10.1080/01443615.2022.2106828

Cited by 2 publications

(2 citation statements)

References 30 publications

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“…MO is associated with female sexual dysfunction (FSD), which is characterised by hypoactive sexual desire disorder, sexual aversion disorder, sexual arousal disorder, orgasmic disorder and sexual pain disorders [ 12 ]. This is in addition to disorders affecting libido, pleasure, reproduction [ 13 , 14 ], intimacy, affection and self-care [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Sexuality and self-concept of morbidly obese women who are sexually attracted to men after bariatric surgery: a phenomenological study

Granero-Molina,

Jiménez-Lasserrotte,

Arias Hoyos

et al. 2024

BMC Women's Health

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Background Morbid Obesity (MO) is a public health problem that affects a person’s physical, psychological and sexual well-being. Women with MO are affected by their body image and self-concept, and obesity stigma may affect women in social and sexual relationships. Objective To describe and understand the experiences of morbidly obese heterosexual women (who are sexually attracted to men) in relation to their body image and sexuality after bariatric surgery. Methodology Qualitative study using Merleau-Ponty’s hermeneutic phenomenology as a philosophical framework. Data collection took place between 2020 and 2021 in a southern Spanish province. A total of 22 in-depth interviews were conducted using open-ended questions until data saturation was reached. Results Two main themes were identified: (1) “Escaping from a cruel environment”: weight loss to increase self-esteem; with the sub-themes: ‘I love myself now’, and ‘Body image and social relationships; a vicious circle; (2) “Now, I am truly me”: accepting my body to reclaim my sexuality, with the sub-themes: ‘The body as the focal point of sexuality’, and ‘When regaining your sex drive reignites your sex life and relationship’. Conclusion Weight loss and body acceptance radically change morbidly obese women’s sex lives after bariatric surgery. They rediscover their bodies, have increased self-esteem, and see improvements in their social relationships and sexuality. These women feel seen, loved and desired, and now value their body image and femininity. As they go through continuous improvements following bariatric surgery, they gradually regain self-esteem, acceptance of their bodies and control over their sex life. Even though the women’s partners benefit from these improvements, they seem to be afraid of being left.

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Section: Introductionmentioning

confidence: 99%

Sexuality and self-concept of morbidly obese women who are sexually attracted to men after bariatric surgery: a phenomenological study

Granero-Molina,

Jiménez-Lasserrotte,

Arias Hoyos

et al. 2024

BMC Women's Health

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“…[5,6]. As with undernutrition, overnutrition negatively affect fertility [7]. Obesityrelated pregnancy complications increase the risk of preterm birth, miscarriage, gestational diabetes, and hypertensive disorders and fetal programming alterations, leading to long-term health issues in offspring [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

The role of dietary patterns in the polarization of angiogenic uterine Natural Killer cells during murine pregnancy

Salles,

Zavan,

Marcelino

et al. 2024

Preprint

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Uterine Natural Killer (uNK) cells, predominant leukocytes in mouse and human pregnant uteruses, play crucial roles in angiogenesis and pregnancy protection. In mice, DBA lectin-reactive uNK cells expressing Gal-N-Ac sugar exhibit angiogenic functions essential for pregnancy maintenance. This study compares the impact of different nutritional imbalances on mouse pregnancy and the activation of angiogenic DBA+ uNK cells to safeguard against pregnancy complications. High Fat (HF), High Carbohydrate (HC), High Protein (HP), and Food Restriction (FR) diets were administered from gestation day (GD) 1 to GD10 or until parturition. HF and HC diets led to reduced expression of DBA-identified N-acetyl-D-galactosamine, akin to LPS-induced inflammation, and decreased uNK perforin levels. Additionally, HF and HC diets resulted in elevated endometrial cleaved caspase-3 and decreased smooth muscle alpha-actin, causing blood vessel wall thinning without jeopardizing pregnancy term. FR impaired uNK differentiation, manifesting as an "all-or-none" phenomenon with 50% pregnancy failure. Our findings highlight the intricate relationship between nutritional imbalances and mouse pregnancy outcomes. Notably, high-fat diets elicited pronounced responses from DBA+ uNK cells, while high-protein diets had relatively weaker effects. This study underscores the importance of comprehending uNK cell dynamics in maintaining pregnancy homeostasis under diverse dietary conditions, paving the way for elucidating molecular mechanisms governing these interactions. By shedding light on these complex relationships, this research offers valuable insights for improving maternal and fetal health in the context of nutritional interventions during pregnancy.

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The impact of obesity on fertility and sexual function in women of child bearing age

Cited by 2 publications

References 30 publications

Sexuality and self-concept of morbidly obese women who are sexually attracted to men after bariatric surgery: a phenomenological study

Sexuality and self-concept of morbidly obese women who are sexually attracted to men after bariatric surgery: a phenomenological study

The role of dietary patterns in the polarization of angiogenic uterine Natural Killer cells during murine pregnancy

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