The impact of probiotic yogurt consumption on lipid profiles in subjects with mild to moderate hypercholesterolemia: A systematic review and meta-analysis of randomized controlled trials

Therapeutic, Prophylactic, and Functional Use of Probiotics: A Current Perspective

“…According to a recent meta-analysis investigation, probiotic yogurt consumption induces a substantial reduction in total and low-density cholesterol levels among patients characterized by mild to moderate hypercholesterolemia. On the other hand, probiotic yogurt did not exert any valuable impact on high-density lipoprotein cholesterol levels ( Pourrajab et al, 2020 ).…”

How strong is the evidence that gut microbiota composition can be influenced by lifestyle interventions in a cardio-protective way?

“…Probiotics are one group of dietary ingredients or food supplements that are widely used to modify the gut microbiota. In several recent meta-analyses including subjects with mild to moderate hypercholesterolemia, these agents have been demonstrated to improve lipid metabolism, particularly to lower the total and LDL-cholesterol [64][65][66][67]. Another group of nutraceuticals that has been of interest with regard to cardiovascular health is fish oil.…”

The effect of probiotics on the serum lipid levels in non-obese healthy adults with hyperlipidemia: A systematic review and meta-analysis of randomized controlled trials

“…For the HDL-C group, there were two independent trials which could make a difference in the results. Both heterogeneity and CES changed when the second period of Fuentes et al (18) was removed (I 2 from 57 % to 0 %, WMD 95 % CI from 0.00 (-0.02, 0.02) to -0.01 (-0.02, -0.00)); heterogeneity changed but the CES was kept consistent when There had been studies (29)(30)(31)(32)(33) on the effect of probiotics in patients with hyperlipidemia before, but most of the studies did not consider the impact of obesity, which is a disorder of metabolism that can affect serum lipid. In addition, Pourrajab et al (31) only used yogurt without considering a capsule.…”

“…With the advantage of probiotics, there are numerous clinical trials (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28) assessing the use of probiotics for the treatment of hyperlipidemia. Some systematic reviews (29)(30)(31)(32)(33) have supported their hyperlipidemia role built on randomized controlled trials, though their results have some limitations. For example, the studies they included in their reviews are often evaluating other primary diseases, making their results less rigorous.…”