There is a huge carbon pool in the lakeside, which is sensitive to environmental changes and can very easily be transformed into a carbon source as land from the lake is reclaimed. In this paper, West Mauri Lake was employed as a case study to examine soil organic carbon (SOC) and its controlling factors along the lakeside. Four transects of land use (i.e., vegetation) types along the landward lakeside were identified as the fluctuation zone, the beach zone, the mesozoic farmland rewetting zone and the xerophytic farmland rewetting zone. With the increase in soil depth, SOC in the lakeside decreased significantly (p < 0.05). SOC had an obvious seasonal variation (p < 0.001), ranking in order: winter (December) > spring (February) > summer (May). Among the aforementioned transects, SOC density differed significantly (p < 0.05), showing a significant increasing trend. Pearson correlation indicated that most soil physiochemical factors showed a significant correlation with SOC (p < 0.01), except total chromium, total copper, total zinc and total phosphorus. The relationship between SOC density and total nitrogen (N) has an obvious “S” curve, and total N accounts for 81% of the variation of SOC, suggesting that total N is the main controlling factor of SOC in the lakeside. The significant difference in SOC along the different vegetation (land use) types implied that land use affects the SOC in the lakeside. The long-term accumulation of N fertilizer after the man-made reclamation and aquaculture obviously controls SOC in the lakeside of West Mauri Lake.