“…The 0-antigen of V. paraha?moZyticus is a lipopolysaccharide containing glucose,glucosamine,heptose,phosphorous,fatty acid ester and nitrogen compounds (229).Lipopolysaccharide from A.sobria and V.anguiZZarm were recently shown to be similar and to contain a dideoxyamino sugar in their core oligosaccharide (230).The toxicity of these LPSs has not been determined but may be low for vertebrates, Interestingly,endotoxin from various sources as well as histamin were shown to enhance pathogenicity of crude hemolytic culture filtrate of A.hydrophiZa in red leg disease in frogs (8).Serotonin and histamin were shown to enhance and aggravate the symptoms of V.parUhu?mo2yticus food poisoning (231 …”