“…At a fundamental level, core mode LP 0,1 to cladding mode LP 0,n coupling takes place when phase-matching condition, λ resonance = (n eff, core -n eff, cladding )Λ, is satisfied [12], where, λ resonance is the coupling resonance wavelength of the cladding mode, n eff, core and n eff, cladding are respective effective indices of the core and the cladding modes, and Λ is grating period. The dependence of λ resonance on n eff, core and n eff, cladding makes SMF-LPG an excellent candidate for sensitive index transduction platform [13][14][15][16][17][18][19][20][21][22][23]. Compared with other techniques such as absorption spectroscopy, electrochemical methods, and mass spectrometry, the LPG has both the sensitivity and ease for in-line systems integration for label free measurement.…”