The Isolation and Characterisation of Emetine Alkaloid From Hedera Helix

Mahran, G. H.; Hilal, S. H.; El-Alfy, Taha S.

doi:10.1055/s-0028-1097773

Cited by 23 publications

(14 citation statements)

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“…The sap of ivy may cause dermatitis in man (Cooper & Johnson 1984), the allergens being the polyacetylenes falcarinol and didehydrofalcarinol (García et al . 1995); skin reactions have also been attributed to the alkaloid emetine (Mahran et al . 1975).…”

Section: Structure and Physiologymentioning

confidence: 99%

Hedera helix L.

Metcalfe

2005

J Ecology

128

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Araliaceae, Schefflereae. Climbing, sometimes reaching 30 m, or prostrate and creeping, forming extensive carpets. Woody stems up to 25 cm diameter, young twigs pubescent with stellate to peltate hairs, and densely furnished with adventitious roots. Leaves petiolate, simple, alternate, exstipulate, coriaceous, glabrous, evergreen; those of climbing or creeping stems 4-10 ( − 25) cm, palmately lobed with 3 -5 triangular, entire lobes; leaves of flowering stems 6 -10 cm, entire, ovate or rhombic. Leaves shining, dark green above, often with pale veins, paler green below; may become pale green/ yellow in late summer, and upper surface sometimes tinged with purple in winter. Flowers actinomorphic, c. 20 in terminal globose umbels, which may be arranged into panicles. Sepals 5, very small, deltate. Petals 5( − 6), yellowish-green, 3 -4 mm, triangular-ovate, somewhat hooded at apex; free. Flowers hermaphrodite, stamens 5; ovary inferior, 5-celled, styles joined into a column. Nectar secreted by a domed disk surrounding the styles. Peduncle, pedicels and receptacle stellate-tomentose; pedicels not jointed. Fruit a berry, bluish-or greenishblack (rarely yellow or white), globose, 6-8 mm. Pulp purple, seeds 1-5, c . 35 mg dry mass, rugose, whitish; embryo small, endosperm ruminate.There is considerable disagreement over the taxonomy of the ivies ( Hedera spp.), with the number of European species being cited as between one and six. Three subspecies of Hedera helix L. (hereafter 'ivy') are recognized in Fl. Eur.: ssp. helix , ssp. poetarum and ssp. canariensis . ' Hedera hibernica ' ('Irish ivy') is recognized only as a horticultural form that is somewhat intermediate between H. helix ssp. helix and ssp. canariensis . Stace (1997) places ssp. canariensis with H. algeriensis Hibberd, and recognizes ' H. hibernica ' as a subspecies of H. helix -ssp. hibernica (G. Kirchn.) D.C. McClint, along with ssp. helix (the common British ivy) and the yellow-fruited garden-escape ssp. poetarum Nyman, from the Mediterranean. Recent molecular data suggest that ssp. helix and ssp. hibernica may represent distinct species, with ssp. helix being the (diploid) maternal parent of the tetraploid ssp. hibernica (Ackerfield & Wen 2003). They are distinguishable by their cpDNA phylogeny, by their trichome morphology and by aspects of their ecology (McAllister 1981;McAllister & Rutherford 1990;Ackerfield & Wen 2002, 2003Grivet & Petit 2002). Throughout this account Irish ivy will be treated as ssp. hibernica of H. helix , as in much of the older literature the subspecies concerned have not been distinguished. Hundreds of cultivars of H. helix and its subspecies are recognized in the horticultural trade.

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Section: Structure and Physiologymentioning

confidence: 99%

Hedera helix L.

Metcalfe

2005

J Ecology

128

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“…Emetine alkaloid was separated for the first time from the alcoholic extract of the four varieties of Hedera helix growing in Egypt. The presence of the alkaloid was investigated by applying IR, UV, NMR and MS analyses [17]. Another innovative, sensitive and accurate method for the isolation and quantification of emetine alkaloid is the RP-HPLC [15].…”

Section: Acta Biologica Hungarica 68 2017mentioning

confidence: 99%

Chemical composition and antifungal activity of Hedera helix leaf ethanolic extract

Roşca-Casian

Mircea

Vlase

et al. 2017

Acta Biologica Hungarica

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The 50% ethanol extract obtained from Hedera helix leaves was investigated regarding the presence and quantity of polyphenols, sterols and in vitro antifungal activity against phytopathogenic fungi. The chemical analysis revealed the presence of rutin, quercetin and kaempferol in the non-hydrolysed sample and quercetin and kaempferol in the hydrolysed sample and stigmasterol in the ivy leaf extract (nonhydrolysed sample). The antifungal activity against phytopathogenic fungi (Aspergillus niger, Botrytis cinerea, B. tulipae, Fusarium oxysporum f. sp. tulipae, Penicillium gladioli, and Sclerotinia sclerotiorum) was assessed using an agar dilution assay. The results are expressed as the minimum inhibitory concentration (MIC = 10-14%) and were compared to a synthetic antifungal drug - fluconazole (MIC = 8-30%). This report presents the first screening of the antifungal activity of the ivy leaf extract on these plant pathogenic fungi species, aiming to use the ivy leaf extract for controlling different diseases of vegetables and ornamental plants, in addition to human disorders.

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“…These compounds, such as the neurotoxic falcarinol, may play an additive role, but this is not clear at present. Some varieties of H. helix in Egypt also appear to contain the alkaloid emetine (Mahran et al 1975) (Figure 12.5). In some instances, fruit pulp, especially when unripe, has shown cyanogenic potential (Barnea et al 1993).…”

Section: Distribution and Habitat-species And Varieties Ofmentioning

confidence: 99%

Araliaceae Juss.

Коляда¹

2012

Toxic Plants of North America

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The Isolation and Characterisation of Emetine Alkaloid From Hedera Helix

Cited by 23 publications

References 0 publications

Hedera helix L.

Hedera helix L.

Chemical composition and antifungal activity of Hedera helix leaf ethanolic extract

Araliaceae Juss.

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