The Left Superior Longitudinal Fasciculus within the Primary Sensory Area of Inferior Parietal Lobe Plays a Role in Dysgraphia of Kana Omission within Sentences

Shinoura, Nobusada; Midorikawa, Akira; Onodera, Tatsuhiro; Yamada, Ryuzo; Tabei, Yusuke; Onda, Yasumitsu; Itoi, Chihiro; Saito, Seiko; Yagi, Kazuo

doi:10.1155/2012/561427

Cited by 5 publications

(4 citation statements)

References 33 publications

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“…This patient’s tumor impinged on the LSLF, with symptoms manifesting as impairment in phonetic writing (Kana script). These symptoms resolved post surgery after the pressure was relieved (Shinoura et al, 2012). Corroborating evidence from DTI showed that the tract had been compressed by the tumor.…”

Section: Discussionmentioning

confidence: 99%

Effects of bilingualism on white matter integrity in older adults

et al. 2018

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Bilingualism can delay the onset of dementia symptoms and has thus been characterized as a mechanism for cognitive or brain reserve, although the origin of this reserve is unknown. Studies with young adults generally show that bilingualism is associated with a strengthening of white matter, but there is conflicting evidence for how bilingualism affects white matter in older age. Given that bilingualism has been shown to help stave off the symptoms of dementia by up to four years, it is crucial that we clarify the mechanism underlying this reserve. The current study uses diffusion tensor imaging (DTI) to compare monolinguals and bilinguals while carefully controlling for potential confounds (e.g., I.Q., MMSE, and demographic variables). We show that group differences in Fractional Anisotropy (FA) and Radial Diffusivity (RD) arise from multivariable interactions not adequately controlled for by sequential bivariate testing. After matching and statistically controlling for confounds, bilinguals still had greater axial diffusivity (AD) in the left superior longitudinal fasciculus than monolingual peers, supporting a neural reserve account for healthy older bilinguals.

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Section: Discussionmentioning

confidence: 99%

Effects of bilingualism on white matter integrity in older adults

et al. 2018

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“…Fibers of the dorsal IFOF, important for reading and writing tasks, coordinate with the SLF to transmit word images between the frontal, parietal, and inferior temporal lobes. Damage to the left SLF in the region of the primary sensory area of the IPL has been shown to cause omission of graphemes (kana and kanji characters) within sentences, or dysgraphia, whereas apraxic dysgraphia usually occurs secondary to damage of the SPL (Shinoura et al., ). Interestingly, these areas are disproportionately large in humans compared to other primates (Orban, Van Essen, & Vanduffel, ).…”

Section: Discussionmentioning

confidence: 99%

White matter connections of the inferior parietal lobule: A study of surgical anatomy

et al. 2017

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IntroductionInterest in the function of the inferior parietal lobule (IPL) has resulted in increased understanding of its involvement in visuospatial and cognitive functioning, and its role in semantic networks. A basic understanding of the nuanced white‐matter anatomy in this region may be useful in improving outcomes when operating in this region of the brain. We sought to derive the surgical relationship between the IPL and underlying major white‐matter bundles by characterizing macroscopic connectivity.MethodsData of 10 healthy adult controls from the Human Connectome Project were used for tractography analysis. All IPL connections were mapped in both hemispheres, and distances were recorded between cortical landmarks and major tracts. Ten postmortem dissections were then performed using a modified Klingler technique to serve as ground truth.ResultsWe identified three major types of connections of the IPL. (1) Short association fibers connect the supramarginal and angular gyri, and connect both of these gyri to the superior parietal lobule. (2) Fiber bundles from the IPL connect to the frontal lobe by joining the superior longitudinal fasciculus near the termination of the Sylvian fissure. (3) Fiber bundles from the IPL connect to the temporal lobe by joining the middle longitudinal fasciculus just inferior to the margin of the superior temporal sulcus.ConclusionsWe present a summary of the relevant anatomy of the IPL as part of a larger effort to understand the anatomic connections of related networks. This study highlights the principle white‐matter pathways and highlights key underlying connections.

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“…They found that the positive sites (i.e., sites at which stimulation caused interference with writing) were mostly located along the superior temporal gyrus (Brodmann's areas 22 and 42). Other authors found that the SLF was related to dysgraphia in a neurosurgical patient [51].…”

Section: Further Exploratory Neuroanatomical Analysismentioning

confidence: 91%

Pre-Surgery Cognitive Performance and Voxel-Based Lesion-Symptom Mapping in Patients with Left High-Grade Glioma

Guarracino

Ius

Baiano

et al. 2021

Cancers

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(1) Background: The literature on the effects of high-grade glioma (HGG) growth on cognition is still scarce. (2) Method: A consecutive series of 85 patients with HGG involving the left hemisphere underwent an extended neuropsychological evaluation prior to surgery. Voxel-based lesion-symptom mapping (VLSM) was used to identify regions related to cognitive performance. (3) Results: The patients’ mean level of pre-surgery accuracy was overall high. They showed the greatest difficulties in language with tasks such as naming (42.1% of patients impaired on nouns and 61.4% on verbs), reading (36.3% on words and 32.7% on pseudo-words), auditory lexical decisions (43.9%) and writing (41.3%) being most frequently impaired. VLSM analysis revealed anatomically separated areas along the temporal cortex and the white matter related to impairments on the different tasks, with voxels commonly shared by all tasks restricted to a small region in the ventral superior and middle temporal gyrus. (4) Conclusions: High-grade glioma affects cognition; nonetheless, lesions do not cause diffuse deficits but selectively impact the different language sub-domains along the ventral stream and the dorsal stream for language processing.

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The Left Superior Longitudinal Fasciculus within the Primary Sensory Area of Inferior Parietal Lobe Plays a Role in Dysgraphia of Kana Omission within Sentences

Cited by 5 publications

References 33 publications

Effects of bilingualism on white matter integrity in older adults

Effects of bilingualism on white matter integrity in older adults

White matter connections of the inferior parietal lobule: A study of surgical anatomy

Pre-Surgery Cognitive Performance and Voxel-Based Lesion-Symptom Mapping in Patients with Left High-Grade Glioma

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