The longitudinal association of changes in diurnal cortisol features with fasting glucose: MESA

Dias, Jenny Pena; Joseph, Joshua J.; Kluwe, Bjorn; Zhao, Songzhu; Shardell, Michelle; Seeman, Teresa E.; Needham, Belinda L.; Wand, Gary S.; Kline, David; Brock, Guy; Castro‐Diehl, Cecilia; Golden, Sherita Hill

doi:10.1016/j.psyneuen.2020.104698

Cited by 29 publications

(22 citation statements)

References 32 publications

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“…During fasting, the levels of cortisol alter. Alterations differ based on measurement time ( 20 , 21 ). With regard to RF, there is a lack of information on how cortisol is altered during RF, particularly when fasting is performed in the summer time for about 17 to 18 h daily.…”

Section: Introductionmentioning

confidence: 99%

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

et al. 2021

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Ramadan fasting (RF) is a type of diurnal intermittent fasting. Previous studies reported the benefits of RF in healthy subjects on mood and health related to quality of life (QoL). Cortisol and brain-derived neurotrophic factor (BDNF) have been shown to play a role in mood, body composition parameters, and health-related QoL. This study aimed at elucidating the mechanism of the benefit of RF, particularly cortisol and BNDF and their association with mood and QoL. Insulin growth factor-1 (IGF-1), interleukin (IL)-8, matrix metalloproteinase (MMP)-9, and myoglobin were determined. Thirty-four healthy men and women were recruited. Serum from peripheral venous blood samples was collected at five time points: 1 week before RF (T1); mid of RF (T2), last days of RF (T3), 1 week after RF (T4), and 1 month after RF (T5). The amounts of biological mediators in the serum samples were determined by enzyme-linked immunosorbent assay (ELISA) and Luminex assays. BDNF and cortisol significantly decreased at T3 (p < 0.05) and T4 (p < 0.001) compared to T1, respectively. It seems the benefits of RF for mood-related symptoms are mediated by different biological mediators, particularly cortisol and BDNF.

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Section: Introductionmentioning

confidence: 99%

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

et al. 2021

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“…If the patients evaluated in this study had been prescribed an antidiabetic agent, we would have needed to exclude the effect of the antidia-betic agent on GA levels. We reckoned that the physiological effects of GH on blood glucose levels are greater in nondiabetic patients than in diabetic patients, and it is easier to understand the relationship between GH and glucose metabolism because patients with DM have higher plasma glucagon and cortisol levels than patients with normal glucose tolerance [21,22]. We can exclude the unexpected effects of counterregulatory hormones if only nondiabetic patients are included in this study.…”

Section: Discussionmentioning

confidence: 99%

Increased glycated albumin levels in patients with acromegaly related to glucose fluctuation caused by growth hormone excess but not albumin metabolism

2022

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Acromegaly is often complicated by impaired glucose tolerance. The accuracy of glycated hemoglobin (HbA 1c ) and glycated albumin (GA) levels in representing glycemic profiles in patients with endocrine disorders, such as acromegaly, is unclear. This retrospective study reviewed data from patients whose GA levels had been recorded. 14 patients with acromegaly without diabetes mellitus (DM) (the acromegaly group), 15 patients with severe adult GH deficiency without DM (the growth hormone deficiency (GHD) group), and 55 nondiabetic patients (the control group) were included in this study. GA levels were significantly increased in the acromegaly group compared with the control and GHD groups, but no significant differences were observed between the control and GHD groups. The three groups were matched using propensity score matching (13 patients with acromegaly, 13 with GHD, and 13 control patients). Nonetheless, the results after matching were the same as those before matching. GA levels in the acromegaly group were significantly associated with plasma glucose (PG) levels at 0, 30, and 120 min after a 75-g oral glucose tolerance test (OGTT). Further, GH levels at 120 min after a 75-g OGTT in the acromegaly group were significantly correlated with GA levels and the difference in PG levels at baseline and 30 min. Our findings suggest that increases in PG levels attributable to excess GH after glucose loading are related to increases in GA levels in patients with acromegaly without DM. Hence, both HbA 1c and GA should be checked to accurately assess impaired glucose tolerance in patients with acromegaly.

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“…The effect of cortisol hormone on regulation of bio-molecular metabolisms shown in many of metabolic pathway ,commonly pathway is stimulate liver and muscle glycogenolysis and gluconeogenesis which occurs as a result of the action of cortisol . Glycogenolysis and gluconeogenesis are metabolic processes lead to increase of serum glucose level that can development of DM severity then lead to un-control serum glucose level (6) . The present study results confirm elevation of serum cortisol level in un-control DM type 2 patients who suffer of depression when compared with control DM type 2 patients .…”

Section: Discussionmentioning

confidence: 99%

Effect of Stress Hormone on Development of Diabetes Mellitus Type 2 Disease

Mohammed¹

2021

JUSST

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Subject :Diabetes Mellitus (DM) is most common disease characterized by elevation of serum glucose level due to impair insulin production called type 1 DM or impair cell response to insulin called type 2 DM .Cortisol is the steroid hormone that secretion by adrenal gland and it’s consider as stress hormone , act many important role in humane body such as regulation of immune system and metabolic process . Objective of the Study: Role of cortisol in development of DM type 2 disease. Materials and Methods: This study was done on 30 patients with un-control DM type2 patients and 30 control DM type 2 patients , the all subjects age within this study were more than 50 years of both genders .After obtained serum , immediately used quantity method for measured level of serum cortisol concentration . Results: This study shows elevation of serum cortisol concentration level in uncontrol DM type 2 group compare with control DM type 2 group. Conclusion: This study confirms that serum cortisol concentration level can act as support DM type 2 disease .

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The longitudinal association of changes in diurnal cortisol features with fasting glucose: MESA

Cited by 29 publications

References 32 publications

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

Ramadan Fasting in Germany (17–18 h/Day): Effect on Cortisol and Brain-Derived Neurotrophic Factor in Association With Mood and Body Composition Parameters

Increased glycated albumin levels in patients with acromegaly related to glucose fluctuation caused by growth hormone excess but not albumin metabolism

Effect of Stress Hormone on Development of Diabetes Mellitus Type 2 Disease

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