The Loss or Inactivation of Pure Gossypol in a Mixed Diet

The Effect of Free Gossypol on Chick Growth

“…This undoubtedly accounts for some of the apparent discrepancies indicated above. Heywang, Bird and Kupperman (1952) mixed pure gossypol with a practical ration and after 144 hours were able to detect only about 20 to 25 percent of the added gossypol by chemical means. Feeding trials confirmed the conclusion that the gossypol had been destroyed or inactivated.…”

Egg Production, Diet Consumption, and Live Weight in Relation to the Free Gossypol Content of the Diet

“…Because of the instability of pure gossypol (Heywang, Bird and Kupperman, 1952) raw decorticated cottonseed and cottonseed meals were used as sources of free gossypol by Heywang, Bird and Altschul (1954) in experiments on the dietary level at which free gossypol causes discolorations in egg yolks. Because of the instability of pure gossypol (Heywang, Bird and Kupperman, 1952) raw decorticated cottonseed and cottonseed meals were used as sources of free gossypol by Heywang, Bird and Altschul (1954) in experiments on the dietary level at which free gossypol causes discolorations in egg yolks.…”

Relationship between the Weight of Chicks and Levels of Dietary Free Gossypol Supplied by Different Cottonseed Products

“…Because of the loss or inactivation of pure gossypol in a mixed diet after it has stood for several days (Heywang, Bird and Kupperman, 1952), pure gossypol was mixed in the diets every other day and the diets fed only on the day of mixing and the following day. Records of feed consumption were kept at intervals of two and seven days.…”

“…What might appear to be contradictory results had been obtained by Boatner and co-workers (1948), in whose experiments pure gossypol had little effect on the growth of chicks. That those results are attributable to the inactivation of free gossypol in the mixed diets due to the infrequent mixing of the diets is indicated by the data of Heywang, Bird and Kupperman (1952).…”