The management of degloving injuries of the limb with full thickness skin grafting using vacuum sealing drainage or traditional compression dressing: A comparative cohort study

Yuan, Kaiming; Zhao, Bin; Cooper, Tokai B; Jin, Zeyuan; Zhou, Xijie; Chen, Xinglong; Li, Zhijie; Gao, Weiyang; Yan, Hede

doi:10.1016/j.jos.2019.01.002

Cited by 12 publications

(13 citation statements)

References 21 publications

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“…If the wound is not treated in time or the treatment method is incorrect, it may even cause amputation, leading to lifelong disability of the patient. e repeated infection of the wound not only causes delayed healing of the defect wound, but in severe cases, bacteria invade the blood circulation and multiply, causing sepsis and threatening the life of the patient [17,18]. erefore, the treatment of skin and soft tissue defect of hand and foot cannot be ignored.…”

Section: Discussionmentioning

confidence: 99%

Clinical Application of Artificial Dermis and Autologous Skin in Repairing Skin and Soft Tissue Defects of Hands and Feet with Bone Exposure Injuries

Song

Lei

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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Patients with skin and soft tissue defects are very common. Mild trauma often causes mild skin damage, while severe injuries are often accompanied by bone and tendon exposure, which brings great pain to patients. For the defect of skin and soft tissue, the traditional treatment methods are mostly medium or full-thickness skin or skin flap transplantation. These methods are effective in wound repair, but there are still many problems. In recent years, with the improvement of tissue engineering technology, the use of artificial skin to repair various skin wounds is gradually becoming clinical, and the key technology of skin tissue engineering lies in the development of dermal substitutes. The appearance of artificial dermis not only solves the shortage of autologous skin source but also makes the operation simple and easy. The purpose of this study was to investigate the clinical effect of artificial dermis combined with autologous skin grafts in repairing hand and foot skin and soft tissue defects with bone exposure. The results show that the use of artificial dermis combined with autogenous blade thick skin to treat patients with hand and foot soft tissue injury with bone exposure has a good clinical effect, and the skin is alive and has fewer complications, which is worthy of promotion.

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Section: Discussionmentioning

confidence: 99%

Clinical Application of Artificial Dermis and Autologous Skin in Repairing Skin and Soft Tissue Defects of Hands and Feet with Bone Exposure Injuries

Song

Lei

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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“…After the red blood cells (RBCs) interacted with nanomaterials, its morphological change was a vital factor to evaluate the hemocompatibility of nanomaterials for bioapplications. RBCs presented fragmentation or aggregation indicating that incompatible nanomaterials interacted with RBCs [43]. The RBCs interacted with pure PBS which presented a normal circular shape (Fig.…”

Section: Morphology Of Erythrocytes and Coagulation Testmentioning

confidence: 96%

Study on a novel poly (vinyl alcohol)/graphene oxide-citicoline sodium-lanthanum wound dressing: Biocompatibility, bioactivity, antimicrobial activity, and wound healing effect

Liu

Zhang

Zhou

et al. 2020

Chemical Engineering Journal

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“…Entire lower extremity degloving injuries are very serious and potentially limb-threatening soft tissue lesions that have a high risk of infection, which can cause life-threatening complications. Although several studies have demonstrated therapeutic methods for reconstruction, few studies have examined the clinical course of patients in a time sequence [1,2]. The primary concern for saving lives in cases of extensive degloved injuries is dealing with acute bleeding and hemodynamic instability.…”

Section: Discussionmentioning

confidence: 99%

Treatment Strategy for Entire Lower Extremity Degloving Injury: A Case Series

Yoon¹,

Jeon

Lim

2022

J Wound Manag Res

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Degloving injuries over the entire lower extremities may result in significant complications such as infection and may even lead to death. Therefore, the establishment of an effective treatment strategy is important. In this study, we propose a treatment strategy after examining cases of patients with entire lower extremity degloving injuries. A retrospective analysis was conducted on three patients who were all treated according to the established strategy. We divided the strategy into three time sequences: initial treatment; intensive medical care and wound bed preparation for skin graft; and skin graft. The patients’ progress was assessed to demonstrate the efficacy of the strategy. Three female patients with no underlying diseases were included, and the mean age was 58.0±15.7 years (range, 44–75 years). The mean C-reactive protein level was the highest on day 3 after the injury and sharply reduced up to day 14.3 on average. After treatment, joint motion was limited in all cases, but it gradually improved with rehabilitation. Unfortunately, all patients suffered from post-traumatic stress disorders. We established a treatment strategy for patients with entire lower extremity degloving injury using a comprehensive approach and achieved satisfactory results.

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The management of degloving injuries of the limb with full thickness skin grafting using vacuum sealing drainage or traditional compression dressing: A comparative cohort study

Cited by 12 publications

References 21 publications

Clinical Application of Artificial Dermis and Autologous Skin in Repairing Skin and Soft Tissue Defects of Hands and Feet with Bone Exposure Injuries

Clinical Application of Artificial Dermis and Autologous Skin in Repairing Skin and Soft Tissue Defects of Hands and Feet with Bone Exposure Injuries

Study on a novel poly (vinyl alcohol)/graphene oxide-citicoline sodium-lanthanum wound dressing: Biocompatibility, bioactivity, antimicrobial activity, and wound healing effect

Treatment Strategy for Entire Lower Extremity Degloving Injury: A Case Series

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