1982
DOI: 10.1016/s0161-6420(82)34841-1
|View full text |Cite
|
Sign up to set email alerts
|

The Marcus Gunn Pupil in Experimental Tract Lessons

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

2
3
0

Year Published

1982
1982
2022
2022

Publication Types

Select...
6
1

Relationship

1
6

Authors

Journals

citations
Cited by 19 publications
(5 citation statements)
references
References 5 publications
2
3
0
Order By: Relevance
“…Our results correlate well with the morphologic lesions seen in a human case [Unsold and Hoyt, 1980] and with the clinical findings [O'Connor et al, 1982] indicating that the pattern of fibers in the optic nerves and tracts is similar in man and the rhesus monkey. This similarity makes the rhesus a good experimental model for research into conditions involving retina, optic nerves and optic tracts.…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
“…Our results correlate well with the morphologic lesions seen in a human case [Unsold and Hoyt, 1980] and with the clinical findings [O'Connor et al, 1982] indicating that the pattern of fibers in the optic nerves and tracts is similar in man and the rhesus monkey. This similarity makes the rhesus a good experimental model for research into conditions involving retina, optic nerves and optic tracts.…”
Section: Discussionsupporting
confidence: 89%
“…The surgical procedures and clinical measurements of pupillary responses have been previously described [O'Connor et al, 1982]. 7 months following surgery the animal was anesthetized with Nembutal and killed by perfusion with 2,500 ml 5% dextrose followed by 3,000 ml of cold Karnovsky's fixative.…”
Section: Methodsmentioning
confidence: 99%
“…Similar studies have been reported by O'Connor et al 16 That the afferent pupillary defect seems to be depen¬ dent solely on the degree of visual field abnormality can be seen by the fact that an afferent pupillary defect developed in patient 1 in our series only after an incomplete homonymous hemianopia progressed to become complete, and patient 9 showed disap¬ pearance of an afferent pupillary defect as a complete homonymous hemianopia resolved into an incom¬ plete defect. Similarly, those patients with incongruous, incomplete field defects were all free of afferent defects except the patient with decreased acuity.…”
Section: Pupillary Abnormalitiessupporting
confidence: 91%
“…These data challenge the hypothesis that a mild asymmetry of 53% of crossed fibers compared with 47% of uncrossed fibers 32 underlies the RAPD seen in optic tract injury. [33][34][35][36] Although asymmetry of fiber crossing at the chiasm is the most plausible explanation for an RAPD with optic tract lesions, as many as 4 other possible explanations are possible: (1) the amount of crossing may be greater than previously estimated, (2) the asymmetry may be greater for pupillomotor fibers, 37 (3) a functional asymmetry may be present that is not represented in anatomical studies, or (4) additional physiologic processes such as inhibition may be playing a role. Nevertheless, optic tract lesions can be associated with RAPDs of 0.3 log units, and a threshold effect might allow for an RAPD to be present in the setting of small amounts of asymmetric injury to the anterior visual pathways.…”
Section: Commentmentioning
confidence: 99%