Qualitative research is becoming more prominent in medicine and health care. Recently, editorials advocating a larger role for qualitative research as a way to address both "clinical" and "biopsychosocial" phenomena have appeared in, for example, the Journal of General Internal Medicine , 1 the Annals of Internal Medicine , 2 and the British Medical Journal . 3 Increasing numbers of reports from qualitative studies have begun to appear in these and other prominent journals.Physicians and clinical and health services researchers, however, may be unfamiliar with qualitative research and unsure how it relates to their interests. The evidencebased medicine movement has taught that clinical practice and health policy should be based on critical review of the best available evidence. 4 To appreciate the evidence supplied by qualitative research, one must be able to address the general question: What are the goals of qualitative research? Principles of evidence-based medicine and behavioral sciences that further suggest that to review any study critically, one must be able to answer several more specific questions: Is the design of the study appropriate to its goals? How valid are its results? How well do they apply to one's practice or circumstances?Unfortunately, the discussion of qualitative research in the medical literature provides no easy answers to these questions. Rather, it reveals considerable controversy, if not confusion about how qualitative research can address either "clinical" or "biopsychosocial" questions. Thus, in this article we try to raise and discuss these questions based on our reading of some of the relevant literature. We hope that the resulting dialogue will contribute to the clarification of their answers, and help physicians and clinical and health services researchers to understand some of the limitations and potential contributions of qualitative research better.
WHAT ARE THE GOALS? Addressing Clinical QuestionsThere is controversy about whether qualitative research can address and answer not only clinical but also biopsychosocial research questions. In their Journal of General Internal Medicine editorial, Berkwits and Aronowitz argued for the broad clinical applicability of qualitative research: "qualitative primary care research aims to identify the essential component parts of clinical phenomena," and is "especially suited to areas that have both social and clinical dimensions." 1 They suggested, for example, that qualitative research can identify "essential and fundamental" cardiovascular risk factors, leading to "a better understanding of which aspects of individual and group behavior and physiology 'hang together' and which are amenable to population interventions, individual behavior change, or physiologic manipulation." However, they did not explain how qualitative research could be used to answer specific clinical questions about cardiovascular risk, or more generally, how it could answer other traditional clinical questions about etiology, diagnosis, prognosis, or therapy. They...