The modulatory effects of ellagic acid and vitamin e succinate on TCDD‐induced oxidative stress in different brain regions of rats after subchronic exposure

Abstract

The original article to which this Erratum was published online 27 November 2004 in Wiley InterScience

Ellagic acid confers protection against gentamicin-induced oxidative damage, mitochondrial dysfunction and apoptosis-related nephrotoxicity

“…EA was shown to have regulatory effects on cellular GSH content in brain tissues through induction of c-glutamylcysteine synthetase. [40] The antioxidant enzymes such as SOD and CAT play central role in cellular antioxidative defence. SOD is responsible for catalysing the dismutation of superoxide radicals to form hydrogen peroxide (H 2 O 2 ).…”

Ellagic Acid Prevents Cisplatin‐Induced Oxidative Stress in Liver and Heart Tissue of Rats

“…Flavonoids have many functions such as phenolic antioxidants, scavengers of free radicals, chelating agents, and modifiers of various enzymatic and biological reactions [36]. Ellagic acid is a naturally occurring plant polyphenol [18,19] that exhibits antioxidative properties both in vivo [21,22] and in vitro [37]. In fact, ellagic acid has been shown to exert a potent scavenging action on both O 2 and · OH, as well as lipid peroxidation [38].…”

“…Ellagic acid (2,3,7,8tetrahydroxy [1]-benzopyrano [5,4,3-cde][1]benzopyran-5,10-dione) is a phenolic constituent in certain fruits and nuts, such as raspberries, strawberries, walnuts, longan seed, mango kernel [18,19] and pomegranate [20]. Ellagic acid has a variety of biological activities including potent antioxidant [21,22], anticancer [23] and antimutagen [24] properties. Although the molecular mechanism of ellagic acid is not entirely known, its potent scavenging action against − OH and O 2 − might be responsible for these effects [25].…”

Effects of quercetin and chrysin on 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin induced hepatotoxicity in rats

“…2,3,7,8‐Tetracholorodibenzo‐ p ‐dioxin (TCDD) is a ubiquitous environmental contaminant which produces some adverse and biochemical effects in experimental animals (Alsharif and Hassoun,2004; Hassoun et al,2004). Much of the concern with exposure to TCDD is due to their environmental and biological persistence, which may result in the bioconcentration and bioaccumulation of the chemicals up to the food chain (Guo et al,2001).…”