The neuronal basis of feeding in the snail, Helisoma, with comparisons to selected gastropods

Murphy, A. D.

doi:10.1016/s0301-0082(00)00049-6

Cited by 57 publications

(67 citation statements)

References 102 publications

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“…Motor neurons in these ganglia control movements of the feeding musculature and associated structures, namely, the radula, odontophore, and corresponding tensor muscles. Neuron 19, a hyperretractor motor neuron, and neuron 110, a retractor motor neuron (Murphy, 2001), are readily accessible electrophysiologically with intracellular recording electrodes through the ganglion sheath (Fig. 2 A).…”

Section: Resultsmentioning

confidence: 99%

“…Dissection methods have been described previously (Haydon and Zoran, 1991). Two buccal neurons, both of which innervate radular tensor muscle groups (Kater, 1974;Zoran et al, 1989), were used for these studies: neurons 19 and 110 (previously B19 and VB10, respectively; see Murphy, 2001). They were identified based on their size, position, and pigmentation.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Transient Electrical Coupling Delays the Onset of Chemical Neurotransmission at Developing Synapses

Szabo

Faber²,

Zoran³

2004

J. Neurosci.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Transient Electrical Coupling Delays the Onset of Chemical Neurotransmission at Developing Synapses

Szabo

Faber²,

Zoran³

2004

J. Neurosci.

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“…Interestingly, the contraction of the CM is strongly influenced by the degree of satiation of the animal (Balaban 2002). Feeding-induced arousal and food intake in snails are regulated to a large extent by serotonergic 5-hydroxytryptamine (5-HT) and dopaminergic neurons (Murphy 2001, Elliott & Susswein 2002. FMRFamide and FMRFamide-containing pleural neurons both inhibit feeding and facilitate withdrawal behaviour in various gastropod species (Kyriakides & McCrohan 1989, Murphy 1990, Alania et al 2004.…”

Section: Gastropodsmentioning

confidence: 99%

The role of RFamide peptides in feeding

Bechtold

Luckman

2007

Journal of Endocrinology

118

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In the three decades since FMRFamide was isolated from the clam Macrocallista nimbosa, the list of RFamide peptides has been steadily growing. These peptides occur widely across the animal kingdom, including five groups of RFamide peptides identified in mammals. Although there is tremendous diversity in structure and biological activity in the RFamides, the involvement of these peptides in the regulation of energy balance and feeding behaviour appears consistently through evolution. Even so, questions remain as to whether feedingrelated actions represent a primary function of the RFamides, especially within mammals. However, as we will discuss here, the study of RFamide function is rapidly expanding and with it so is our understanding of how these peptides can influence food intake directly as well as related aspects of feeding behaviour and energy expenditure.

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“…In Helisoma and Lymnaea, it is possible to define three phases for feeding motor patterns, corresponding to protraction, retraction, and hyperretraction (Murphy, 2001;Elliott and Susswein, 2002). A study of 22 motor neurons in reduced preparations of Aplysia during ingestive-like and egestive-like motor patterns demonstrated that there was a clear boundary between protraction and retraction in the synaptic inputs to the motor neurons, but many subcomponents of the motor output could be distinguished [Church and Lloyd (1994), their Fig.…”

Section: Implications For Pattern Generationmentioning

confidence: 99%

Neuromechanics of Coordination during Swallowing inAplysia californica

Morton

Chiel

2006

J. Neurosci.

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Bernstein (1967) hypothesized that preparation of the periphery was crucial for correct responses to motor output. To test this hypothesis in a behaving animal, we examined the roles of two identified motor neurons, B7 and B8, which contribute to feeding behavior in the marine mollusk Aplysia californica. Neuron B7 innervates a hinge muscle and has no overt behavioral effect during smaller-amplitude (type A) swallows, because the hinge muscle is too short to exert force. Neuron B8 activates a muscle (I4) that acts solely to grasp material during type A swallows. During larger-amplitude (type B) swallows, the behavioral actions of both motor neurons change, because the larger-amplitude anterior movement of the grasper sets up the periphery to respond differently to motor outputs. The larger anterior movement stretches the hinge muscle, so that activating neuron B7 mediates the initial retraction phase of swallowing. The changed position of the I4 muscle allows neuron B8 not only to induce grasping but also to pull material into the buccal cavity, contributing to retraction. Thus, larger-amplitude swallows are associated with the expression of two new degrees of freedom (use of the hinge to retract and use of the grasper to retract) that are essential for mediating type B swallows. These results provide a direct demonstration of Bernstein's hypothesis that properly positioning the periphery can be crucial for its ability to correctly respond to motor output and also demonstrate that biomechanical context can alter the functions of identified motor neurons.

show abstract

The neuronal basis of feeding in the snail, Helisoma, with comparisons to selected gastropods

Cited by 57 publications

References 102 publications

Transient Electrical Coupling Delays the Onset of Chemical Neurotransmission at Developing Synapses

Transient Electrical Coupling Delays the Onset of Chemical Neurotransmission at Developing Synapses

The role of RFamide peptides in feeding

Neuromechanics of Coordination during Swallowing inAplysia californica

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