The Occurrence of Brain Tumors in Several Members of a Family*

Familial aggregation of astrocytoma in northern Sweden: An epidemiological cohort study

“…Some studies show an increased risk ratio (Choi et al, 1970;Wrensch et al, 1997), but this was not confirmed in other studies (Preston-Martin et al, 1989;Wrensch and Barger, 1990). The findings are inconsistent, and currently no site-specific hereditary or familial astrocytoma has been identified, apart from several case reports of multiple astrocytoma (Kjellin et al, 1960;Ikizler et al, 1992).…”

Malignant gliomas occurring in identical twins

“…The histological nature of the gliomas is not recorded. Kjellin et al (1960) reported twin brothers who both had astrocytomas of the right temporal lobe. The age of onset in one twin was 33 years and in the other 50 years.…”

Case-Control Study of Neuroepithelial Tumors in Rochester, Minnesota, 1950–1977

“…Case reports and genetic studies indicate that certain families may be more prone to the development of gliomas [15][16][17][18][19]. Accu rate information on family history is, how ever, severely limited when abstracting solely from medical histories.…”