THE OVARIAN THECA CELL Part IV–The Hyperthecosis Syndrome

Shippel, S.

doi:10.1111/j.1471-0528.1955.tb14148.x

Cited by 79 publications

(2 citation statements)

References 47 publications

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“…Among the non‐neoplastic causes, ovarian hyperthecosis is an unusual cause 2 . There have been only eight previous reported cases of androgenetic alopecia as a result of ovarian hyperthecosis in postmenopausal women 2–9 . This disorder, however, may not be as rare as previously thought.…”

Section: Introductionmentioning

confidence: 98%

Androgenetic alopecia in a postmenopausal woman as a result of ovarian hyperthecosis

Kim

Marjoniemi²,

Diamond

et al. 2003

Aust J Dermatology

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A 65-year-old woman presented with an 8-year history of progressive frontotemporal alopecia and hirsutism. She had elevated serum levels of testosterone, androstenedione and estradiol. Ultrasound and computed tomography imaging suggested a right ovarian mass, while bilateral ovarian venous sampling demonstrated increased testosterone levels originating from both ovarian veins. Histology obtained following bilateral oophorectomy demonstrated bilateral ovarian hyperthecosis. Six months after surgery, the patient remains well with no progression of the alopecia. Ovarian hyperthecosis is a rare cause of androgenetic alopecia in postmenopausal women. The role of hyperthecosis and its relationship to androgenetic alopecia is reviewed.

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Section: Introductionmentioning

confidence: 98%

Androgenetic alopecia in a postmenopausal woman as a result of ovarian hyperthecosis

Kim

Marjoniemi²,

Diamond

et al. 2003

Aust J Dermatology

View full text Add to dashboard Cite

show abstract

“…Another anatomic substrate of hirsutism is provided by folIicuIar cysts with hyperplasia of theca ce1ls.l. 3.49 9.271 35,42 Whether this disorder represents merely a variant of the Stein-Leventhal syndrome is not entirely clear but such was the interpretation of Morns and It is the purpose of this paper to draw attention to a syndrome that combines a distinct abnormality of both ovaries (hypertrophy and diffuse luteinization) best defined as pseudothecoma, associated with endometrial carcinoma in a cushingoid clinical setting of obesity, diabetes, hirsutism, and hypertension. It is the opinion of the writers that this entity should be isolated from thecomas of the ovary and from the Stein-Leventhal syndrome with or without luteinization of cyst lining.…”

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confidence: 99%