“…In addition, North et al (1999) also found evidence of an east-west cline using spatial autocorrelation analysis on a subset of these anthropometric data. Evidence of this cline is not limited to anthropometric variation; an east-west difference has also been detected in studies of blood groups (Hackett et al, 1956;Hackett and Dawson, 1958;Dawson, 1964;Tills et al, 1977), phenylalanine hydroxylase (PAH) haplotypes (O'Donnell et al, 2002), and Y-chromosome markers (Hill et al, 2000). Several explanations have been offered to explain the east-west cline, including continuation of a Neolithic dispersal across Europe into and across Ireland (Hill et al, 2000;O'Donnell, 2002), successive waves of migrants displacing previous inhabitants and pushing them westward (Hooton et al, 1955;North et al, 1999), and the concentration of migrants from England and Wales in the north and east of Ireland over the past 400 years (Tills et al, 1977;Relethford and Crawford, 1995).…”