The physiology of growth hormone in poultry

Scanes, Colin G.; Hall, T.R.; Harvey, S.

doi:10.1016/0739-7240(84)90001-8

Cited by 28 publications

(19 citation statements)

References 84 publications

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“…A major regulatory role by GH is not likely to stimulate IGF-I synthesis in chick embryogenesis, since GH levels have been reported to be low until after hatching, a pattern opposite that of IGF-I (15,16). The possibility that PRL, which also shows a peak in midembryogenesis in chicken serum (10,35), has an influence on the regulation of IGF-I secretion remains.…”

Section: Discussionmentioning

confidence: 91%

“…While previous studies had provided some information on serum IGF-I in late chicken embryos (14)(15)(16) as well as in culture medium from chick embryo hepatocytes (23) and cartilage (24) D, and E). In A, a normal embryo is starting to break the shell on day 21.…”

Section: Discussionmentioning

confidence: 97%

“…In addition, a simple model of growth retardation by means of culturing the embryo ex ovo (12) allows excellent access to the embryo for observation and to the vessels for blood sampling. We have previously found that the unfertilized chicken egg yolk contains IGF-I of maternal origin (13), and others have detected immunoreactive IGF-I in chicken embryo vitreous humor (14) and late stage embryo serum (15,16). Further, IGF-I receptors are present in multiple tissues of the chicken embryo during organogenesis and in the whole embryo from the first day of development onward (8,17).…”

mentioning

confidence: 91%

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Insulin-Like Growth Factor-I Serum Levels Show a Midembryogenesis Peak in Chicken That Is Absent in Growth-Retarded Embryos Culturedex Ovo*

1991

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Insulin-like growth factor-I (IGF-I) is the primary mediator of GH action after birth, but its role as a regulator of prenatal growth is unclear. In a previous study we showed that IGF-I mRNA was expressed in chicken embryos beginning at the blastoderm stage (day 0, newly laid egg). Here we present the ontogeny of serum IGF-I in normal and growth-retarded chicken embryos. Serum samples were pooled from multiple embryos starting on day 4 of development in ovo until hatching (day 21). Extracts of day 2 and 3 whole embryos were also studied. IGF-binding proteins were removed by filtration on Sep-Pak C-18 cartridges. IGF-I was quantitated by a heterologous RIA validated for chicken species. Embryonic IGF-I showed a HPLC profile similar to that of adult chicken serum IGF-I. Serum IGF-I was measurable on day 6 of development (approximately 0.04 ng/ml), reached a peak on day 15 (18 ng/ml), and decreased to a low concentration (0.2 ng/ml) the day before hatching. Embryos cultured ex ovo showed progressive growth retardation after day 10 of development, and by day 20 their weight was 50% of normal. The serum IGF-I concentration of ex ovo cultured embryos was normal on day 10, but remained low until day 21, without the midembryogenesis rise observed in normal embryos. These results support the concept that IGF-I may have a role in general embryonic growth in addition to any paracrine/autocrine action in individual tissues.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 97%

mentioning

confidence: 91%

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Insulin-Like Growth Factor-I Serum Levels Show a Midembryogenesis Peak in Chicken That Is Absent in Growth-Retarded Embryos Culturedex Ovo*

1991

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“…Plasma levels of GH are high in young birds and low in the adult (Scanes and Lauterio, 1984). Higher levels of circulating GH have been measured in laying hens compared to incubating hens (Bedrak et al, 1981) and in young chickens which are fasted (Scanes, 1987). Conversely, it has been shown that both the pituitary content and synthetic rate of GH is significantly increased in incubating hens compared to laying hens.…”

mentioning

confidence: 84%

“…(Scanes, 1987), and short-term fasting results in increased GH secretion in young chickens (Scanes, 1987) and turkeys (Proudman and Opel, 1981). Since incubation behaviour is associated with aphagia and a 20-30% decrease in body weight (Zadworny et al, 1985(Zadworny et al, , 1988, it has been proposed by Hoshino and Wakita (1989) (fig 3).…”

Section: Rna Dot Blot Analysismentioning

confidence: 99%

Changes in expression of the prolactin and growth hormone gene during different reproductive stages in the pituitary gland of turkeys

Karatzas

Guemene²,

Zadwomy³

et al. 1997

Reprod. Nutr. Dev.

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Summary ― The changes in levels of prolactin (PRL) and growth hormone (GH) in plasma and the pituitary gland and their transcripts were measured in turkey hens at different physiological stages by radioimmunoassay and dot blot hybridization analysis, respectively. The levels of tPRL mRNA in the pituitary gland increased from those of the immature group to the egglaying group, reaching a maximum during the incubation and a minimum during the moulting stages. Changes in pituitary levels of PRL and PRL mRNA followed a similar trend and consequently were highly correlated (r 2 = 0.83), whereas a significant but lower correlation was observed between circulating and pituitary levels (r 2 = 0.62). Less significant changes were measured for tGH mRNA, with maximum and minimum levels measured in the pituitaries of egglaying and non-laying hens, respectively. These data suggest that although changes in con

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Growth hormone secretion from chicken adenohypophyseal cells in primary culture: Effects of human pancreatic growth hormone-releasing factor, thyrotropin-releasing hormone, and somatostatin on growth hormone release

Perez

Malamed

Scanes

1987

General and Comparative Endocrinology

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The physiology of growth hormone in poultry

Cited by 28 publications

References 84 publications

Insulin-Like Growth Factor-I Serum Levels Show a Midembryogenesis Peak in Chicken That Is Absent in Growth-Retarded Embryos Culturedex Ovo*

Insulin-Like Growth Factor-I Serum Levels Show a Midembryogenesis Peak in Chicken That Is Absent in Growth-Retarded Embryos Culturedex Ovo*

Changes in expression of the prolactin and growth hormone gene during different reproductive stages in the pituitary gland of turkeys

Growth hormone secretion from chicken adenohypophyseal cells in primary culture: Effects of human pancreatic growth hormone-releasing factor, thyrotropin-releasing hormone, and somatostatin on growth hormone release

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