The post-operative analgesic effects of epidurally administered morphine and transdermal fentanyl patch after ovariohysterectomy in dogs

Pekcan, Zeynep; Koç, Bahattin Taylan

doi:10.1111/j.1467-2995.2010.00571.x

Cited by 32 publications

(26 citation statements)

References 26 publications

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“…Several studies have reported the high analgesic efficacy and long duration of action of ED morphine 2,5,19,20 . Nevertheless, a few published studies have described the analgesic properties and the efficacy of extradural tramadol in dogs 10,17 .…”

Section: Discussionmentioning

confidence: 99%

A comparison of extradural tramadol and extradural morphine for postoperative analgesia in female dogs undergoing ovariohysterectomy

et al. 2012

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PURPOSE: To compare the postoperative analgesic effects of the extradural tramadol or morphine in female dogs undergoing ovariohysterectomy. METHODS: Sixteen female dogs were randomly assigned to two groups of eight animals each and received morphine (0.1mg kg-1 M group) or tramadol (2mg kg-1 T group). The pre-anesthetic medication was intravenously (iv) acepromazine (0.05mg kg-1). Anesthesia was induced with propofol (4mg kg-1iv) and maintained with isoflurane. The degree of analgesia was evaluated using a numerical rating scale that included physiologic and behavior variables. Dogs were scored at one, three, six and 12 hours after surgery by one blinded observer. Dogs were treated with morphine (0.5mg kg-1) if their scores were >6. Serum cortisol was measured before the pre-anesthetic medication was administered (basal), at the time of the ovarian pedicle clamping (T0), and at 1 (T1), 6 (T6) and 12 (T12) hours postoperative. RESULTS: The pain score did not differ between morphine and tramadol treatments. Rescue analgesia was administered to one dog in the T treatment group. Serum cortisol did not differ between treatments. CONCLUSION: The extradural administration of morphine or tramadol is a safe and effective method of inducing analgesia in female dogs undergoing ovariohyterectomy.

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Section: Discussionmentioning

confidence: 99%

A comparison of extradural tramadol and extradural morphine for postoperative analgesia in female dogs undergoing ovariohysterectomy

et al. 2012

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“…This increase in cardiac parameters is dangerous if the cardiac reserves are low. Increased cardiac load requires a higher level of oxygen, and if the coronary arteries do not pump the required amount of blood to the heart, myocardial infarction occurs [4,[8][9][10] .…”

Section: Why Should Analgesics Be Used?mentioning

confidence: 99%

“…Some of the adverse effects associated with the use of these drugs are bradycardia, respiratory depression, hypotension, agitation and emesis. Although opioids are generally feared to have serious side effects, in contrast to human beings, cats and dogs seem to be remarkably resistant to these side effects, and serious side effects are surprisingly rare when these agents are used with care [8,11,27] . For example, opioid induced-bradycardia is generally not lifethreatening and usually does not require treatment.…”

Section: Opioidsmentioning

confidence: 99%

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Nasıl Daha İyi Anestezi Kombinasyonları Yapılabilir? Güncel Bilgilerin İncelenmesi

Pekcan¹

2016

Kafkas Univ Vet Fak Derg

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In the ever-developing world, the recent years have brought about a wide range of novelties and significant developments in the fields of veterinary anaesthesia and analgesia. In the not-too-distant past, it was believed that the pain threshold of animals was high and that pain was not felt by animals during surgery, when they were anaesthetised. It was considered that the only analgesic drugs that could be used during operation were non-steroidal anti-inflammatory drugs. Today, these suppositions are all accepted as fallacies across the world, and it is well-known that the administration of analgesic drugs should be started in the preoperative period. This article describes pain in animals, how pain perceived by the operated animal can be recognised, and if not treated, to which complications pain may lead. Furthermore, in the last part of the manuscript, complications associated with the use of atropine and α2-agonist combinations, and the adverse effects of anaesthesia-induced hypotension are also explained. This review is intended to provide an insight into recently developed novel practices and to elucidate some main issues, which may be confusing for the veterinary practitioner. Keywords: Anaesthesia, Analgesia, Pain, Cat, Dog Nasıl Daha İyi Anestezi Kombinasyonları Yapılabilir? Güncel Bilgilerin İncelenmesi ÖzetGelişen dünya ile beraber son zamanlarda veteriner anestezi ve analjezi alanında da pek çok değişiklikler, yenilikler ve ilerlemeler kaydedilmiştir. Eskiden hayvanların ağrı eşiklerinin yüksek olduğuna ve operasyon sırasında anestezi altında iken ağrının hissedilmediğine inanılırdı. Operasyon sırasında tek kullanılabilecek analjezik ilacın nonsteroidal antiinflamatuvar olabileceği düşünülüyordu. Bu inanışların yanlış olduğu artık tüm dünyada kabul edilmektedir, analjezik ilaçların uygulanmasına preoperatif dönemde başlanması gerekliliği bilinmektedir. Bu makalede, hayvanlardaki ağrı, operasyon sırasında gelişen ağrının nasıl anlaşılabileceği ve tedavi edilmediği takdirde gelişebilecek komplikasyonlar anlatılmıştır. Ayrıca, makalenin sonunda atropin ile α2-agonist kombinasyonlarının komplikasyonları ve anestezi sırasında oluşan hipotansiyonun yan etkileri üzerinde de durulmaya çalışılmıştır. Bu derleme ile veteriner hekimlerin kafalarında karışıklık yaratan bazı konulara ışık tutulması, son yıllarda gelişen yeni uygulamalara ve ilaç kombinasyonlarına yer verilmesi amaçlanmıştır.

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“…Visually checking the air bubble in the syringe for compression, the injection was made slowly without any resistance. After the dogs were maintained in a slight head-down tilt position (approximately 200) for 10 minutes, they were turned in to supine position (7,8).…”

Section: Epidural Anesthesia Proceduresmentioning

confidence: 99%

Comparison of the effects of lidocaine and fentanyl in epidural anesthesia in dogs

Saritas¹,

Sarıtaş²,

Pamuk³

et al. 2014

BLL

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Abstract:The study included 12 clinically healthy, adult male dogs of various breeds, admitted to our clinic for castration. After general anesthesia with sevofl urane, we administered epidural fentanyl (1 mcg/kg) to fentanyl group, while lidocaine group was given Lidocaine (3 mg/kg) through epidural administration. When hemodynamic parameters were stabilized, fi rst measurements were recorded at minutes 0, 15, 30, 60 in both groups, which included Heart Rate (HR), body temperature, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), sodium (Na + ), potassium (K + ), glucose (GLC), and hemoglobin (HB) measurements. In addition, serum samples were obtained from arterial blood at the same measurement times, and pH, pO 2 , pCO 2 , HCO 3 , %O 2 Saturation, BE levels were measured. For hematological analysis, WBC, RBC, HCT, THR counts were performed. For serum biochemical analysis, venous blood samples were collected at minutes 0 and 60 and CK, TP, UREA, ALT, AST, ALB, GGT, CRE, CK-MB parameters were assessed using auto-analyzer. Moreover, cortisol levels were measured in the samples collected at minutes 0, 30, and 60. Mean arterial blood pressure values measured at minutes 15, 30 and 60 were found signifi cantly lower in the fentanyl group (p<0.01). In conclusion, we suggest that epidural anesthesia with lidocaine and fentanyl can provide an effective and safe option in high-risk groups (Tab. 5, Fig. 1, Ref. 24). Text in PDF www.elis.sk.

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The post-operative analgesic effects of epidurally administered morphine and transdermal fentanyl patch after ovariohysterectomy in dogs

Cited by 32 publications

References 26 publications

A comparison of extradural tramadol and extradural morphine for postoperative analgesia in female dogs undergoing ovariohysterectomy

A comparison of extradural tramadol and extradural morphine for postoperative analgesia in female dogs undergoing ovariohysterectomy

Nasıl Daha İyi Anestezi Kombinasyonları Yapılabilir? Güncel Bilgilerin İncelenmesi

Comparison of the effects of lidocaine and fentanyl in epidural anesthesia in dogs

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