The prevalence of antibody to human parvovirus B 19 in England and Wales

Cohen, B. J.; Buckley, Meghan

doi:10.1099/00222615-25-2-151

Cited by 308 publications

(210 citation statements)

References 7 publications

Supporting

Mentioning

167

Contrasting

Unclassified

Order By: Relevance

“…It reinforces the importance of prevention of parvovirus B19 infection in pregnant women and especially that of the recent recommendation of the Society of Obstetricians and Gynaecologists of Canada (SOGC) to assess a pregnant woman's immunity to parvovirus B19 [10]. The association of parvovirus B19 seropositivity with age is consistent with population-based studies in the United Kingdom and Australia [11,12]. This trend can be explained by the fact that parvovirus B19 antibodies last for life [10].…”

Section: Discussionsupporting

confidence: 78%

Seroprevalence of parvovirus B19 infection in daycare educators

et al. 2004

View full text Add to dashboard Cite

SUMMARYThis study was undertaken to provide first-time estimates for the seroprevalence of parvovirus B19 infection among daycare educators in Montre´al, Canada, and to identify factors associated with seropositivity. A cross-sectional design was used. Directors and educators from 81 daycare centres (DCCs) were surveyed about DCC and personal characteristics respectively, and serum samples from 477 female educators were tested for parvovirus B19 IgG antibodies. The seroprevalence of parvovirus B19 was 70 %. Parvovirus B19 seropositivity was significantly associated with age and with working experience in DCCs, but the latter association was restricted to educators aged less than 40 years. In conclusion, working as a daycare educator appears to be associated with increased risk of acquiring parvovirus B19 infection, but this finding will require further investigation. Because of the large proportion of educators susceptible to acquiring parvovirus B19 infection, our findings also highlight the need for preventive measures.

show abstract

Section: Discussionsupporting

confidence: 78%

Seroprevalence of parvovirus B19 infection in daycare educators

et al. 2004

View full text Add to dashboard Cite

show abstract

“…B19 infection usually occurs in childhood, whereby Ͼ50% of adults are seropositive (6,7). Viremia in early infection occurs with extremely high titers (up to 10 11 to 10 13 genome equivalents/ml) (1,9).…”

mentioning

confidence: 99%

Detection and Differentiation of Human Parvovirus Variants by Commercial Quantitative Real-Time PCR Tests

Hokynar¹,

Norja²,

Laitinen

et al. 2004

J Clin Microbiol

View full text Add to dashboard Cite

Parvovirus B19 causes a variety of diseases in humans, with outcomes ranging from asymptomatic to severe, such as chronic anemia in immunocompromised patients or fetal hydrops and death after maternal infection during pregnancy. The virus may be transmitted via plasma-derived products. According to the results of solventdetergent safety studies, an upper limit of B19 DNA in plasma pools was recently defined. To restrict the input of B19 virus into production pools, a quantitative nucleic acid test is a prerequisite. We examined the suitability of the two commercial quantitative B19 PCR tests, LightCycler-Parvovirus B19 quantification kit (Roche Diagnostics) and RealArt Parvo B19 LC PCR (Artus) for detection, quantification, and differentiation of the three known B19 genotypes, including the newly described erythrovirus variants (genotypes 2 and 3). The former kit was highly sensitive for genotype 1 but was not suitable for detection of genotype 2 or one of two genotype 3 strains. The latter kit detected and differentiated all three genotypes, albeit with lower sensitivity for one of the genotype-3 strains. We furthermore assessed the prevalence of the three B19 virus genotypes in blood donors, by screening pooled plasma samples derived from 140,160 Finnish blood-donor units. None of the pools contained detectable levels of B19 virus genotypes 2 or 3. The origin, mode of transmission, and clinical significance of these genotypes are unknown and deserve further study. The RealArt Parvo B19 LC PCR is suitable for detection, quantification, and differentiation of all three B19 virus genotypes in molecular and clinical research.

show abstract

“…It sometimes causes more severe manifestations such as arthralgia, transient aplastic crisis in patients with hereditary haemolytic anaemia, prolonged bone marrow suppression in immunocompromised patients and abortion or foetal death if infection occurs during pregnancy [1]. In countries in the temperate zone, parvovirus B19-infections are common in childhood with a peak incidence in the age group 5-15 years [2][3][4].…”

mentioning

confidence: 99%

“…The prevalence of anti B19 IgG antibody in children in Singapore is lower than that in Japan [5,12], Germany [3], USA [4], and England and Wales [2]. It is also lower than that in Brazil [13,14] and Africa [15].…”

mentioning

confidence: 99%

Low prevalence of antibody to human parvovirus B19 in Singapore

et al. 1994

View full text Add to dashboard Cite

SUMMARYA seroepidemiological survey was conducted in Singapore to assess the prevalence of antibody to human parvovirus B19. Sera were collected from 600 healthy individuals between 6 months and over 50 years of age and tested for IgG antibody against B19 virus by antigen capture indirect immunosorbent assay. The overall seropositivity rate was 162 %. All the children under 5 years of age were seronegative. Antibody prevalence increased gradually from 35 % in school children (5-14 years of age) to 7 7 % in age group 15-19 years and then to 103 % in young adults (20-24 years of age). In the age group 25-34 years the prevalence was 28 % and in the age group over 35 years 65 % had parvovirus B19 antibody. The results of the survey indicate that there has been very low incidence of B19 virus infection in Singapore during the last two decades.

show abstract

The prevalence of antibody to human parvovirus B 19 in England and Wales

Cited by 308 publications

References 7 publications

Seroprevalence of parvovirus B19 infection in daycare educators

Seroprevalence of parvovirus B19 infection in daycare educators

Detection and Differentiation of Human Parvovirus Variants by Commercial Quantitative Real-Time PCR Tests

Low prevalence of antibody to human parvovirus B19 in Singapore

Contact Info

Product

Resources

About