The prevalence of clinical factors used for risk assessment of osteoporotic fractures

Скрипникова, И. А.; Guryev, A. V.; Шальнова, С. А.; Деев, А. Д.; Myagkova, M.A.; Индукаева, Е. В.; Толпаров, Г. В.; Grinshtein, Yu. I.; Efanov, А. Yu.; Ilyin, Valentin A.; Кулакова, Н. В.; Nedogoda, S. V.; Романчук, С. В.; Boytsov, S. А.

doi:10.17116/profmed201619532-40

Cited by 16 publications

(7 citation statements)

References 28 publications

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“…Research Article substantially lower in Vladikavkaz [16]. However, the gradual decrease in the frequency of fractures was not revealed, which demonstrates relatively small contribution of climatic and geographical features to the risk of fractures.…”

Section: Estimation Of Bone Fracture Risk Using Frax® Model In Urban mentioning

confidence: 85%

“…Ethnic diversity can also cause significant differences in the prevalence of both the fractures themselves and their risk factors [11,12]. Moreover, significant differences in prevalence of certain risk factors included in FRAX® were detected which contributes individually or collectively towards the estimation of fracture probability [16,17]. Consequently, in order to obtain a complete picture of the prevalence of osteoporotic fractures in the Russian Federation, high quality regional epidemiological studies are necessary.…”

Section: Research Articlementioning

confidence: 99%

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Estimation of bone fracture risk using FRAX model in some regions of Russian Federation

Скрипникова¹,

Myagkova²,

Шальнова³

et al. 2018

Int. J. Clin. Rheumatol

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Keywords: osteoporosis risk factors • 10-year fracture probability • FRAX® • therapeutic intervention threshold • climate and geography effects • basic economic features Purpose: To estimate the absolute risk (AR) of fractures in urban population of some Russian regions using Russia-specific FRAX® model, as well as to evaluate therapeutic intervention threshold (TIT) adopted in Russia.Material and methods: Representative samples of the population from 8 Russian cities included 9143 Russian residents (6324 women and 2819 men) aged 40-69 years (mean age 53.29 ± 0.02 years). AR of fractures was calculated without BMD using the batch processing of data.Results: The average AR of major fractures (MF) was 7.8% (8.9% in women and 5.5% in men, p=0,0001), hip fractures (HF) -0.7% (0.9% in women and 0.4% in men, p=0.0001). In women AR was higher in all age groups across all cities in comparison with that in men both for MF and HF. The proportion of individuals who had a previous fragility fractures was 15.2% and 30.6% from them were determined to be in a highrisk of fractures zone and 69.4% -in the low-risk of fractures zone.Conclusion: The average AR of MF and HF increased with age regardless of participants' gender, and were significantly higher among female population. The majority of the respondents with the previous fragility fractures have been included into the low-risk of fractures zone, which implies the low sensitivity of the TIT currently established for country.

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Section: Estimation Of Bone Fracture Risk Using Frax® Model In Urban mentioning

confidence: 85%

Section: Research Articlementioning

confidence: 99%

Estimation of bone fracture risk using FRAX model in some regions of Russian Federation

Скрипникова¹,

Myagkova²,

Шальнова³

et al. 2018

Int. J. Clin. Rheumatol

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“…и соавт. в другой российской эпидемиологической работе ЭССЕ-РФ, в рамках которой изучались ФР ОП-пере-ломов у мужчин, также был показан высокий процент куря-щих среди опрошенных людей (34,8%) [12]. В то же самое время, распространенность таких ФР, как предшествую-щие переломы, причины вторичного ОП, прием ГК, низкий ИМТ, среди мужчин, участвовавших в нашем анкетирова-нии была в 1,5-2 раза выше по сравнению с результатами, полученными в исследовании ЭССЕ-РФ.…”

Section: Discussionunclassified

“…Оказалось, что высокая забо-леваемость этими переломами в возрасте до 70 лет была связана у них с наличием большего количество ФР, вклю-чая злоупотребление алкоголем, курение и недостаточное потребление кальция с продуктами питания. В ЭССЕ-РФ также было отмечено, что избыточное потребление алко-голя и курение определялись чаще в более молодых воз-растных группах мужчин, чем у лиц старше 60 лет [12].…”

Section: Discussionunclassified

“…Эта программа начала внедряться в россий-скую клиническую практику с 2012г., однако крупномас-штабных исследований по оценке распространенности ФР ОП-переломов, включенных в данный алгоритм, у мужчин, проживающих в различных регионах нашей страны, до по-следнего времени не было. Проведенный поиск выявил лишь одну эпидемиологическую работу, выполненную в 8-ми городах пяти регионов РФ по единому дизайну, в ко-торой были представлены данные о частоте ФР у мужчин в возрасте 40-69 лет, что было отмечено как ограничение данного исследования [12].…”

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Osteoporosis and osteoporotic fractures risk factors in men aged 50 years and older

Nikitinskaya¹,

Торопцова²

2017

Osteopor Bone Dis

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ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой, Москва, Россия Проведен одномоментный скрининг случайных выборок мужчин в возрасте 50 лет и старше, проживавших в пяти городах (Архангельск, Мурманск, Тюмень, Красноярск, Челябинск) 3-х федеральных округов РФ, с целью оценки частоты встреча-емости отдельных факторов риска (ФР) остеопоротических переломов. В результате обследования 1330 мужчин установ-лено, что наиболее распространенными были следующие факторы: курение, низкоэнергетические переломы в анамнезе, вторичные причины ОП, недостаточное потребление кальция с продуктами питания. Мужчины в СФО и СЗФО курили чаще, чем лица из УФО (p=0,0011 и p=0,047, соответственно), распространенность других ФР по регионам не различалась. Осте-опороз по данным периферической рентгеновской денситометрии выявлялся чаще у жителей УФО (26%), чем у мужчин в СЗФО (17%) и СФО (19%). Более 50% мужчин в каждом регионе имели 2 и более ФР, при этом лиц с 3-мя и более ФР было достоверно больше в УФО, а в возрасте 50-59 лет -в СЗФО. 85 % мужчин в этих регионах не получали с продуктами пита-ния адекватного количества кальция.КЛЮЧЕВЫЕ СЛОВА: Остеопороз; факторы риска переломов; потребление кальция с пищей; периферическая рентгенов-ская денситометрия; Cross-sectional screening of random samples of men aged 50 years and older living in five cities (Arkhangelsk, Murmansk, Tyumen, Krasnoyarsk, and Chelyabinsk) from three Federal Districts (FD) of the Russian Federation was conducted to evaluate the frequency of individual risk factors (RF) of osteoporotic fractures among them. Total 1330 men were included in the study. We found that the most common were the following RF: smoking, prior fragility fractures after age 40, secondary causes of OP, insufficient calcium intake. Significantly more smokers were among males in Siberian (S) FD and North -Western (NW)FD compared with those from Ural (U) FD (p=0,0011 and p=0,047, respectively), the frequency of other RF did not differ depending on region. The рprevalence of osteoporosis according to peripheral x-ray densitometry of the proximal forearm was higher among residents of the UFD (26%) than among men in the NWFD (17%) and SFO (19%). More than 50% of men in each region had 2 or more RF, while those with 3 or more RF were significantly more in the UFD at any age, and at the age of 50-59 years -in the NWFD. Calcium intake was inadequate in 85% of the respondents in these regions. OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES RISK FACTORS IN MEN AGED 50 YEARS AND OLDER©

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Risk factors for osteoporosis in men aged 40 years or older: the results of the program «Osteoscreening-Russia»

Никитинская¹,

Торопцова²,

Насонов³

2018

RJTAO

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Objective:to estimate the prevalence of individual risk factors (RFs) for osteoporosis (OP) and fractures, the frequency of high-risk osteoporotic fractures by the Fracture Risk Assessment Tool (FRAXR) and OP according to distal forearm X-ray densitometric findings in men aged 50 years or older in different regions of Russia.Patients and methods.Random cluster proportionally stratified samples of men aged 40 years or older were formed in the district polyclinics of 23 towns of the country with over 100,000 people in the framework of the social program «Osteoscreening-Russia» (OSR). The survey was conducted using a unified questionnaire. Screening also involved a densitometric study of distal forearm bone mineral density using a peripheral X-ray osteodensitometer (Osteometer Meditech DTX-200). The final analysis included 5057 men from 14 towns of 5 federal districts (FDs) of Russia.Results.Estimation of the prevalence of individual RFs for osteoporotic fractures in men aged 40 years or older showed that the most common RFs were insufficient dietary calcium intake (91%), smoking (30%), low-energy fractures in the history (20%), low physical activity (16%), and secondary causes of OP (11%). The men in the Ural FD (UFD), Siberian FD, and Central FD were more frequently found to have ≥3 RFs. 5% of men aged 50 years or older were at high risk for osteoporotic fractures by FRAXR, whereas the frequency of OP according to peripheral densitometric findings was 19%. The inhabitants of the North-Western FD and UFD had the greatest need for medical and preventive measures, which was identified by the FRAXR algorithm.Conclusion.The OSR survey could reveal the most common clinical RFs for OP and osteoporotic fractures in men in 5 regions of the Russian Federation, insufficient dietary calcium intake and assess the risk of osteoporotic fractures and the rate of OP according to peripheral densitometric findings.

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The prevalence of clinical factors used for risk assessment of osteoporotic fractures

Cited by 16 publications

References 28 publications

Estimation of bone fracture risk using FRAX model in some regions of Russian Federation

Estimation of bone fracture risk using FRAX model in some regions of Russian Federation

Osteoporosis and osteoporotic fractures risk factors in men aged 50 years and older

Risk factors for osteoporosis in men aged 40 years or older: the results of the program «Osteoscreening-Russia»

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