The Prevalence of Type 1 Diabetes in Children of Mazandaran Province

Abstract

Introduction: The prevalence of type 1 diabetes in all countries throughout the world is different. In this study, an introduction is, therefore, provided for the development of type 1 diabetes in children in Mazandaran province by using all available resources.Methods: In this descriptive cross-sectional study, the prevalence of patients with initial diagnosis of type 1 diabetes mellitus, aging from 6 months to 18 years, was located through contacting and referring to all organizations of insurers and doctors or experts in children endocrinologist and adolescent diseases in Mazandaran province.Results: 289 patients with type 1 diabetes were identified, 138 of whom were male (47.8%), and 151 were women (52.2%) with an overall prevalence of 0.04%, and the rate of this prevalence was 48 cases among 100000 people (50 cases among 100000 girls and 36 cases among 100000 boys). The mean age of the patients was 11.5 years old. In the study of delivery method, 180 patients (62.3%) were diagnosed with cesarean section, and 109 (37.7%) were born through natural delivery method. The mean age of onset of diabetes was 7 years. The minimum and maximum ages were 7 months and 18 years, respectively. 97 (33.6%) of the patients were also hospitalized for the first time due to ketoacidosis, and were diagnosed with diabetes.Conclusion: Type 1 diabetes in Mazandaran province was more prevalent than the similar study in southern Iran and neighboring countries. It is essential to pay greater attention to this disease through studying it in the other parts of the country.

Trends in incidence rates of childhood type 1 diabetes mellitus: A retrospective study in Isfahan province, Iran

“…In a prospective study that was carried out in Fars province from 21 March 1991 to 20 March 1996, the incidence of type 1 diabetes mellitus among the population aged <30 years was reported to be 3.7 in 100,000, with a significantly higher incidence rate in girls than boys 20 . In another study in Mazandaran, the prevalence of type 1 diabetes mellitus was reported to be 48 in 100,000 among the population aged 18 years 18 . In one recent study from Fars Province, Amiri et al 19 reported the incidence of type 1 diabetes mellitus using the insurance archived prescription for 2 years.…”

“…Providing an epidemiological feature of the disease is a priority for each community for proper allocation of healthcare resources and developing prevention studies. Considering that there were few studies in this field in Iran [17][18][19][20] , we aimed to determine the incidence rate of childhood type 1 diabetes mellitus in Isfahan province and its trend over a period of 12 years. Our findings would help plan nationwide studies in this field.…”

COVID-19 and Diabetes in Children: A Narrative Review

“…Type 1 diabetes (T1DM) is one of the major endocrine disorders in childhood (2). Recent study in Iran showed that it occurs in 48 cases per 100000 people (50 and 36 cases per 100000 girls and boys, respectively) (3).…”

ASSOCIATION OF ANTI-COXSACKIE VIRUS-B IgG WITH AUTOANTIBODIES RELATED TO TYPE 1 DIABETES MELLITUS

“…Specific CVB serotypes are shown to be related to each of the disorders listed above. As an example, CVB3 infections are linked to viral myocarditis and DCM (6) , CVB5 infections are linked to encephalitis and aseptic meningitis outbreaks (7) , and CVB1 is linked to the induction of β-cell autoimmunity, which is linked to T1DM (8) . In type one diabetes, beta cells are destroyed by an antibody that affects the pancreas, leading to the loss of insulinproducing beta cells (9) .…”

“…Diagnosing T1DM from other forms is particularly important in its treatment because it helps with medication selection, evaluation of illness prognosis, and determining the risk of diabetes development in family members of the diabetic patient. T1DM is distinguished from other forms by the presence or absence of insulin production (8) . A large number of autoantibodies have been discovered in pancreatic beta cells, and it has been postulated that these autoantibodies may act significant roles at the beginning of autoimmune islet destruction (7) .…”