1981
DOI: 10.1530/acta.0.0980161
|View full text |Cite
|
Sign up to set email alerts
|

The relationship of plasma gonadotrophins and steroid concentrations to body growth in girls

Abstract: Plasma concentrations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), 17 alpha-hydroxyprogesterone (17\g=a\-OHP),17\g=b\-oestradiol (Oe2) and progesterone (P) were measured in 352 healthy girls aged 6.0 to 15.9 years, as a function of age (CA), weight, height and calculated lean body mass (LBM) and total body fat (TBF). The earliest hormonal changes were a fall in mean plasma FSH concentrations together with a small but significant rise in plasma Oe2 well in advance of any sign of pubertal dev… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
3
0

Year Published

1985
1985
2023
2023

Publication Types

Select...
4
4

Relationship

0
8

Authors

Journals

citations
Cited by 8 publications
(3 citation statements)
references
References 30 publications
0
3
0
Order By: Relevance
“…Additionally, the somatotrophic effect of estrogen replacement is biologically plausible because estrogens are involved in growth. At menarche, increasing circulating levels of estradiol is the initial step, and possibly the triggering step, in the adolescent growth spurt (22). Postmenopausal estrogen therapy is associated with the release of growth hormone and various growth factors (23).…”
Section: Discussionmentioning
confidence: 99%
“…Additionally, the somatotrophic effect of estrogen replacement is biologically plausible because estrogens are involved in growth. At menarche, increasing circulating levels of estradiol is the initial step, and possibly the triggering step, in the adolescent growth spurt (22). Postmenopausal estrogen therapy is associated with the release of growth hormone and various growth factors (23).…”
Section: Discussionmentioning
confidence: 99%
“…27 At menarche, increasing circulating levels of oestradiol are one of the triggers of the adolescent growth spurt, and HRT is associated with release of growth hormone and increasing levels of growth factors. 28,29 High oestrogen levels in menstruating women and postmenopausal HRT users are linked to increased muscle strength. 30,31 Gain in skeletal muscle with HRT was also indirectly demonstrated in an older study measuring urinary creatinine excretion rate, a waste product of muscle metabolism.…”
Section: Menopause and Lean Body Massmentioning
confidence: 99%
“…This represents a percentage of total weight somewhere between 22 and 24%. [16][17][18] Recent hormonal studies suggest the association between a "critical level" of body composition and major hormonal events in boys and girls 19,20 regardless of a cause-effect relationship. The relationships in this study appeared to be more closely related in both sexes to lean body mass than to total body fat, although the two are undoubtedly closely related.…”
mentioning
confidence: 99%