The risk of smoking with stroke in Asia : meta-analysis

Abstract

This study uses a systematic method of review and meta-analysis to look at the risk of smoking with stroke in Asia. Further analysis based on the stroke subtype (ischemic stroke and haemorrhagic stroke was also carried out. Literature search was carried out in the PubMed, EBSCO and Google Scholar databases. Q tests were performed to determine the heterogeneity of included studies. Funnel plot, Egger regression test and trim and fill methods were used to identified publication bias and with the transformation of the model between the fixed effect model and the random effect model for sensitivity analysis A total of 12 articles were included consisting of 9 studies with case control design studies and 3 studies with cohort designs. The meta-analysis results showed that people who smoke have risks pooled OR 2.04 times (95% CI 1.57-2.65) for having a stroke Analysis of the type of stroke, smokers had 2.3 times the risk of having an ischemic stroke or 2.77 times for having a haemorrhagic stroke. Eggers test showed no influence of publication bias on the meta-analysis of smoking with stroke to. From this meta-analysis, it can be concluded that smoking increasing risk for stroke. This study found the risk of smokers to have a haemorrhagic stroke is higher than ischemic stroke.

Faktor Resiko yang Mempengaruhi Kejadian Stroke: Sebuah Tinjauan Sistematis

“…Merokok dapat meningkatkan risiko stroke, Penyebab stroke pada perokok dapat dipicu oleh asap rokok yang mengandung lebih dari 7.000 bahan kimia beracun, bahan kimia ini akan mengubah dan merusak sel-sel diseluruh tubuh, perubahan yang disebabkan oleh bahan kimia ini meningkatkan risiko stroke pada perokok,adapun mekanisme perokok dapat menyebabkan stroke yaitu penurunan aliran darak keotak sehingga menyebabkan vasokontriksi yang memepercepat terjadinya trombus, merokok juga dapat menurunkan HDL dan merusak sel endotel yang menyebabkan ateroma. (Hasnah, Lestari, & Abdiana, 2020). Faktor risiko yang dapat mempengaruhi kejadian stroke yaitu merokok yang dapat menyebabkan perdarahan intraserebral dengan merusak dinding arteri yang pecahnya pembuluh darah.…”

The Dangers of Cigarette Smoke and the Role of Guided Inquiry for Prevention and Other Prevention

“…An analysis by stroke subtype showed that smokers were 2.30 times more likely to have an ischemic stroke than non-smokers and 2.77 times more likely to have a hemorrhagic stroke than non-smokers. Hemorrhagic stroke is bleeding within the brain, and ischemic stroke is caused by the buildup of fatty deposits on the inner lining of blood vessels (Hasnah et al, 2020).…”