The role of climate on the geographic variability of asthma, allergic rhinitis and respiratory symptoms: results from the Italian study of asthma in young adults

Zanolin, Maria Elisabetta; Pattaro, Cristian; Corsico, Angelo Guido; Bugiani, Massimiliano; Carrozzi, Laura; Casali, Lucio; Dallari, Rossano; Ferrari, Marcello; Marinoni, Alessandra; Migliore, Enrica; Olivieri, Mario; Pirina, Pietro; Verlato, Giuseppe; Villani, Simona; Marco, Roberto de

doi:10.1046/j.1398-9995.2003.00391.x

Cited by 77 publications

(57 citation statements)

References 49 publications

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“…Our results confirm [24] that the prevalence of asthma and asthma-like symptoms in Italy is higher in the Mediterranean than in the Sub-Continental area. This difference could reflect the different exposures to outdoor and indoor allergens, or the difference in ozone concentration, which tends to reach higher levels at higher temperatures, or to the interaction between higher temperatures and pollution [20].…”

Section: The Asthma Epidemic In Italysupporting

confidence: 88%

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Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

Marco¹,

Cappa²,

Accordini³

et al. 2011

Eur Respir J

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189

162

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The prevalence of asthma increased worldwide until the 1990s, but since then there has been no clear temporal pattern.The present study aimed to assess time trends in the prevalence of current asthma, asthma-like symptoms and allergic rhinitis in Italian adults from 1990 to 2010.The same screening questionnaire was administered by mail or phone to random samples of the general population (age 20-44 yrs) in Italy, in the frame of three multicentre studies: the European Community Respiratory Health Survey (ECRHS) (1991-1993; n56,031); the Italian Study on Asthma in Young Adults (ISAYA) (1998-2000; n518,873); and the Gene Environment Interactions in Respiratory Diseases (GEIRD) study (2007-2010; n510,494). Time trends in prevalence were estimated using Poisson regression models in the centres that repeated the survey at different points in time.From 1991 to 2010, the median prevalence of current asthma, wheezing and allergic rhinitis increased from 4.1% to 6.6%, from 10.1% to 13.9% and from 16.8% to 25.8%, respectively. The prevalence of current asthma was stable during the 1990s and increased (relative risk 1.38, 95% CI 1.19-1.59) from 1998-2000 to 2007-2010, mainly in subjects who did not report allergic rhinitis. The prevalence of allergic rhinitis has increased continuously since 1991.The asthma epidemic is not over in Italy. During the past 20 yrs, asthma prevalence has increased by 38%, in parallel with a similar increase in asthma-like symptoms and allergic rhinitis.

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Section: The Asthma Epidemic In Italysupporting

confidence: 88%

“…early responders may report more symptoms than late or non-responders). Similar methods were used in previous papers [20,24].…”

mentioning

confidence: 99%

Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

Marco¹,

Cappa²,

Accordini³

et al. 2011

Eur Respir J

Self Cite

189

162

View full text Add to dashboard Cite

show abstract

“…Prevalence of rhinitis in patients with asthma. The majority of patients with asthma experience rhinitis symptoms (277,648,909,937,945,1882,(1888)(1889)(1890)(1891)(1892)(1893)(1894)(1895)(1896)(1897)(1898)(1899). However, in many instances, symptoms may predominate in one organ and be hidden or unrecognized in other organs even though they exist.…”

Section: Epidemiologic Links Between Rhinitis and Asthmamentioning

confidence: 99%

“…Often, it is found that rhinitis prevalence increases faster than asthma prevalence, which was also found to decrease in some countries (904,947,948,1896,(1917)(1918)(1919)(1920)(1921)(1922). It appears that in regions of highest prevalence, the proportion of subjects suffering from asthma or rhinitis may be reaching a plateau (1919).…”

Section: Epidemiologic Links Between Rhinitis and Asthmamentioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,867

1,761

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“…(2) The World Health Organization (WHO) states that climate plays an important role in the transmission of various infectious diseases that are among the leading causes of morbidity and mortality in developing countries. (3) Although several effects of seasonality on public health in areas with a temperatesubtropical climate have been documented, (4)(5)(6)(7)(8) the relationships between health and climate have yet to be understood. (9) Some studies have found a connection between temperature or humidity and the increase in the proportion of respiratory diseases, however, those studies were based on secondary data, which are subject to biases, and this causes concern about their methodological validity and reliability.…”

Section: Introductionmentioning

confidence: 99%

Efeito da sazonalidade climática na ocorrência de sintomas respiratórios em uma cidade de clima tropical

et al. 2011

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ResumoObjetivo: Avaliar o efeito da sazonalidade climática na ocorrência de sintomas respiratórios em uma cidade de clima tropical no Brasil. Métodos: Estudo de corte transversal relacionando dados de indivíduos que procuraram assistência médica em uma Unidade Básica de Saúde na cidade de Goiânia (GO) com dados meteorológicos coletados diariamente. No intervalo de um ano, todos os pacientes que preenchiam os critérios de inclusão foram entrevistados em 44 dias distintos (11 em cada estação) escolhidos aleatoriamente. ANOVA foi usada para a comparação das médias das variáveis dependentes por estação. Correlação foi conduzida entre as variáveis dependentes e cada variável meteorológica. Os efeitos das variáveis meteorológicas foram analisados com um modelo de AutoRegressive Moving Average with eXogenous input (ARMAX, média móvel autorregressiva com entrada exógena). Resultados: Dos 3.354 participantes, 494 (14,6%) apresentavam sintomas respiratórios. A variação de temperatura não foi suficiente para provocar mudanças no número de indivíduos com sintomas respiratórios; porém, houve aumento desse número com baixos níveis de umidade no inverno, com diferença estatisticamente significativa entre as estações (p < 0,01). Foi observado que a média da umidade relativa mínima dos três dias que antecederam as observações correlacionou-se negativamente com o número de indivíduos com sintomas respiratórios (p = 0,04), e um modelo ARMAX incluindo a mesma variável apresentou um coeficiente estatisticamente significativo (p < 0,0001). Conclusões: Nesta amostra, o número de indivíduos com sintomas respiratórios aumentou significativamente com a redução da umidade relativa do ar, e esse aumento pôde ser previsto a partir de dados meteorológicos.Descritores: Estações do ano; Clima tropical/efeitos adversos; Sinais e sintomas respiratórios; Modelos logísticos. AbstractObjective: To evaluate the effect that seasonality has on the occurrence of respiratory symptoms in a Brazilian city with a tropical climate. Methods: This was a cross-sectional study, in which data related to subjects who sought outpatient treatment at a primary health care clinic in the city of Goiânia, Brazil, were correlated with daily meteorological data. Over a one-year period, all the patients who met the inclusion criteria were interviewed on 44 distinct, randomly selected days (11 days per season). We used ANOVA in order to compare the means of the dependent variables by season. Correlations were drawn between each dependent variable and each meteorological variable. The effects of the meteorological variables were analyzed with an AutoRegressive Moving Average with eXogenous input (ARMAX) model. Results: Of the 3,354 participants, 494 (14.6%) had respiratory symptoms. Although temperature variation alone had no effect on the number of individuals with respiratory symptoms, the low levels of humidity during winter resulted in a statistically significant difference among the seasons (p < 0.01). The mean minimum relative humidity on the three days prior to the i...

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The role of climate on the geographic variability of asthma, allergic rhinitis and respiratory symptoms: results from the Italian study of asthma in young adults

Abstract: Asthma prevalence seems to be significantly affected by climate as asthma-like symptoms were more common in central-southern Italy, with a Mediterranean climate, than in areas with a continental climate (northern Italy).

Cited by 77 publications

References 49 publications

Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Efeito da sazonalidade climática na ocorrência de sintomas respiratórios em uma cidade de clima tropical

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