2022
DOI: 10.3390/antiox11122468
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The Role of Lead and Cadmium in Gynecological Malignancies

Abstract: Lead and cadmium are non-essential and toxic heavy metals. Their presence and elevated levels can lead to many pathologies. They disrupt the antioxidant properties of many enzymes, consume the resources of antioxidant cells, and thus participate in the generation of oxidative stress, which may result in DNA damage. In addition, they have been found to be carcinogenic through their genotoxic properties. They have been shown to be present in various types of cancer, including cancer of the female reproductive sy… Show more

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Cited by 7 publications
(4 citation statements)
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“…In both seasons, Cd contributed the highest percentage (58) of the total RR value recorded. Thus, Cd was the metal in the studied sediments with the highest tendency to cause noncarcinogenic health problems on those exposed to these sediments, followed by Pb, [92]. The high Cd enrichment observed in this study is similar to the findings by Wang et al [93] and Liu et al [94].…”
Section: Non-carcinogenic Human Health Risks Evaluationsupporting
confidence: 90%
“…In both seasons, Cd contributed the highest percentage (58) of the total RR value recorded. Thus, Cd was the metal in the studied sediments with the highest tendency to cause noncarcinogenic health problems on those exposed to these sediments, followed by Pb, [92]. The high Cd enrichment observed in this study is similar to the findings by Wang et al [93] and Liu et al [94].…”
Section: Non-carcinogenic Human Health Risks Evaluationsupporting
confidence: 90%
“…Cd contributed the highest proportion (81.4 %) while; Cr donated 0.01 % of the entire RR obtained. Consequently, Cd was the metal with the most devastating tendency to cause both the cancer and non-cancer risks to the consumers of meat from the studied farms (Rahimzadeh et al, 2017;Furtak et al, 2022). The high RR value reported is in agreement with the ones by Kumar and Kumar, (2021) 2020).…”
supporting
confidence: 88%
“…nonetheless, it will take a long time for MTBE to be completely eradicated from contaminated water sources. This chemical molecule, which is present in high amounts in contaminated water, has been related to tumors of the genitalia, kidneys, and gland, as well as leukaemia and lymphoma (Picetti et al, 2022;Furtak et al, 2022).…”
Section: Pollution By Organic Substancesmentioning
confidence: 99%