“…This and other studies showing improvement following IO (Pangrazio-Kulbersh et al, 1999;Ngan and Yiu, 2000;King et al, 2003;Mirabelli et al, 2005;Kerosuo et al, 2008) did not consider the possibility for relapse and other negative consequences from continued facial growth. Therefore, the current study follows children who received interceptive treatment for 2 more yrs, with the finding that the PAR improvement did deteriorate slightly [i.e., 15.4 at completion of IO (Jolley et al, 2010) to 21.0 at 48 mos in this study], but remained significant.…”