The Strength and Elasticity of Bone in Rats on a Rachitogenic Diet

Weir, J. B. De V.; Bell, G. H.; Chambers, John W.

doi:10.1302/0301-620x.31b3.444

Cited by 43 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…to a characteristic length. Contrary to this, interspecific scaling studies indicate that musculoskeletal tissue properties in mammals scale independently of body mass (Weir et al, 1949;Smith and Walmsley, 1959;Currey, 1979;Biewener, 1982;Pollock and Shadwick, 1994b;Medler, 2002). However, ontogenetically within a species, the current study suggests that material properties (Young's modulus) in some tendons do indeed appear to scale as predicted by dynamic similarity.…”

Section: Tendon Stiffness and Materials Propertiescontrasting

confidence: 57%

Ontogenetic scaling of pelvic limb muscles, tendons and locomotor economy in the Ostrich (Struthio camelus)

Channon

Young

Cordner

et al. 2019

Journal of Experimental Biology

View full text Add to dashboard Cite

In rapidly growing animals there are numerous selective pressures and developmental constraints underpinning the ontogenetic development of muscle-tendon morphology and mechanical properties. Muscle force generating capacity, tendon stiffness, elastic energy storage capacity and efficiency were calculated from muscle and tendon morphological parameters and in vitro tendon mechanical properties obtained from a growth series of ostrich cadavers. Ontogenetic scaling relationships were established using reduced major axis regression analysis. Ostrich pelvic limb muscle mass and cross-sectional area broadly scaled with positive allometry, indicating maintained or relatively greater capacity for maximum isometric force generation in larger animals. The length of distal limb tendons was found to scale with positive allometry in several tendons associated with antigravity support and elastic energy storage during locomotion. Distal limb tendon stiffness scaled with negative allometry with respect to body mass, with tendons being relatively more compliant in larger birds. Tendon material properties also appeared to be size-dependent, suggesting that the relative increased compliance of tendons in larger ostriches is due in part to compensatory distortions in tendon material properties during maturation and development, not simply from ontogenetic changes in tendon geometry. Our results suggest that the previously reported increase in locomotor economy through ontogeny in the ostrich is due to greater potential for elastic energy storage with increasing body size. In fact, the rate of this increase may be somewhat greater than the conservative predictions of previous studies, thus illustrating the biological importance of elastic tendon structures in adult ostriches.

show abstract

Section: Tendon Stiffness and Materials Propertiescontrasting

confidence: 57%

Ontogenetic scaling of pelvic limb muscles, tendons and locomotor economy in the Ostrich (Struthio camelus)

Channon

Young

Cordner

et al. 2019

Journal of Experimental Biology

View full text Add to dashboard Cite

show abstract

“…The same results were reported by Salomon & Volpin (1972) in growing rats on low calcium diet which gave lighter and thinner long bones and decreased bending strength of metatarsals with increasing deflection in bending. Weir et al (1949) found decrease of bending strength and stiffness and increase of deflection in rats on a rachitogenic diet even with supplement of vitamin D. They concluded that the effects were depending of, and correlated with, a corresponding decrease in ash volume.…”

Section: Experimental Osteoporosis -Osteopeniamentioning

confidence: 96%

Physical Properties and Chemical Content of Canine Femoral Cortical Bone in Nutritional Osteopenia its Reversibility and the Effect of Fluoride

Romanus

1974

Acta Orthopaedica Scandinavica

View full text Add to dashboard Cite

An apparatus for determination of breaking‐strength of small rodent bones

Felts

1964

Anat. Rec.

View full text Add to dashboard Cite

Analysis of age changes in physical characteristics of mouse limb bones requires a sensitive, consistent and relatively simple apparatus for determination of transverse breaking strength. The developed instrument is essentially a one meter counter‐balanced 4‐to‐1 lever with a tracked, motor‐driven weight on its upper surface. At the beam's short end a loading tool impinges upward on a bone mounted in an adjacent holder; at the opposite end is a mercury switch connected to a relay halting the weight motor when fracture occurs. Bones, with proximal ends embedded in convex securing blocks of impression medium, may be positioned in a standard relationship to the holder, loading tool edge, and the balanced beam. Repetitive loading of a steel spring indicates instrument error of 1.8%. Preliminary tests with a random series of paired mouse femora show no significant difference between left and right bones. In the long‐term study it will be possible to correlate physical strength with other characteristics of opposite bones. An air‐gap capacitor across loading tool and bone holder and coupled to a variable frequency oscillator permits monitoring of specimen elasticity on a strip‐chart recorder.

show abstract

The Strength and Elasticity of Bone in Rats on a Rachitogenic Diet

Abstract: Since bone is primarily a supporting and protecting tissue it seems appropriate to investigate its properties in the same way that an engineer measures the characteristics of 444 THE JOURNAL OF BONE AND JOINT SURGERY

Cited by 43 publications

References 0 publications

Ontogenetic scaling of pelvic limb muscles, tendons and locomotor economy in the Ostrich (Struthio camelus)

Ontogenetic scaling of pelvic limb muscles, tendons and locomotor economy in the Ostrich (Struthio camelus)

Physical Properties and Chemical Content of Canine Femoral Cortical Bone in Nutritional Osteopenia its Reversibility and the Effect of Fluoride

An apparatus for determination of breaking‐strength of small rodent bones

Contact Info

Product

Resources

About