The surprise pathology—Primary squamous cell carcinoma of the colon—A case report

Husain, Aysha Hassan Ali; Kaundinya, Kiran B.; Hammed, Faizal; Sayed, Abdul Rahim Al

doi:10.1016/j.ijscr.2020.05.062

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…SCC of the gastrointestinal tract is common in the esophagus and anus; however, it rarely affects the colon and rectum. The first case of SCC of the colon was described in 1919 [2]. Since then, 150 cases of colorectal SCC have been reported, and 65 cases were found in the English literature [1].…”

Section: Discussionmentioning

confidence: 99%

“…The clinical manifestation of primary SCC of the colon has been described to be comparable to colorectal adenocarcinoma. Frequently reported symptoms include rectal bleeding, abdominal pain, change in bowel habits, weight loss, and bowel obstruction [ 2 ]. In the literature review, we only found three cases describing sigmoid or splenic flexure perforation, but none with cecal perforation [ 7 - 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…Its pathogenesis is not fully understood, but it has been associated with inflammation, infectious processes, exposure to radiation, and squamous differentiation of existing colonic adenomas. It usually presents in the fifth to sixth decades of life and most commonly in women [2].…”

Section: Introductionmentioning

confidence: 99%

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Primary Squamous Cell Carcinoma of the Cecum Presenting as Spontaneous Perforation

Recinos

Mohapatra

Broder

et al. 2020

Cureus

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Squamous cell carcinoma (SCC) of the colon is an extremely rare condition, and its pathogenesis is not fully understood. Bowel perforation is a very infrequent manifestation of colonic SCC, and only a few cases have been reported in the literature involving sigmoid and splenic flexure perforation. To the best of our knowledge, no cases of ileocecal perforation have been documented in the literature. Here we present a case of cecal SCC that presented with bowel perforation, necessitating emergent surgical intervention. Histopathological examination showed SCC with lymph node metastasis. This case reviews current knowledge and highlights the rare manifestation that these rare tumors can present.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Primary Squamous Cell Carcinoma of the Cecum Presenting as Spontaneous Perforation

Recinos

Mohapatra

Broder

et al. 2020

Cureus

View full text Add to dashboard Cite

show abstract

“…SCC of colon has a female preponderance in their 5th and 6th decade of life [ 2 ].It is impossible to differentiate SCC from adeno carcinoma clinically based on symptoms and signs as both have similar presentation. Primary SCC of colon is diagnosed by histopathological confirmation and the tumor should not be in continuity with the anal canal or any fistula lined track with the colon [ 3 ]. Currently, there are no standard treatment guidelines for this condition except complete excision along with lymphadenectomy as done in adenocarcinoma variety.…”

Section: Introduction and Importancementioning

confidence: 99%