The synergistic activity of antibiotics combined with eight traditional Chinese medicines against two different strains of Staphylococcus aureus

Effect of ethanolic extract of Ecballium elaterium against Staphylococcus aureus and Candida albicans

“…In order to assess the effect of combinations of ethanolic extract and antibiotic, the MIC values for antibiotic were determined to be as a reference point for defining the interactions [26] . Synergistic effects resulting from the combination of antibiotics with various plant extracts have been studied earlier against MRSA or MSSA [27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] . From this study, ethanolic extract of E. elaterium fruits is very efficient in treating infectious diseases caused by MRSA and may also helpful for treating diseases caused by C. albicans.…”

“…Exposure to light was avoided to prevent the loss of effective ingredients. Approximately [30][31][32][33][34][35][36][37][38][39][40] g of dried material were mixed thoroughly with magnetic stirrer in 200 mL of 80% ethanol at room temperature and the mixture left for 24 h. The insoluble materials were removed by centrifugation at 10 000 rpm for 10 min at 4 曟. Then, the extract was evaporated to dryness at 37 曟.…”

Antibiotic Resistance and the Prospects of Medicinal Plants in the Treatment of Salmonellosis

“…The ethanol extracts of the Chinese plants, Isatis tinctoria and Scutellaria baicalensis in combination with ciprofloxacin had synergistic activities against antibiotic resistant S. aureus (Yang et al, 2005). The combinations of pencillin with ethanolic extracts of Paederia scandens and Taraxacun monlicum showed a strong bactericidal activity on two strains of S. aureus (Yang et al, 2005). When Ciprofloxacin was incorporated at sub-inhibitory concentrations (1/8MIC) to the crude chloroform extracts of Jatropha elliptica and the mixture assayed against NorA expressing S. aureus, the activity of the extract was enhanced.…”

“…The bactericidal activity of the combination of PGME (0.1×MIC) with ampicillin (0.5×MIC) by time-kill assays, reduced cell viability b 99.9 and 72.5% in MSSA and MRSA populations, respectively (Braga et al, 2005). The ethanol extracts of the Chinese plants, Isatis tinctoria and Scutellaria baicalensis in combination with ciprofloxacin had synergistic activities against antibiotic resistant S. aureus (Yang et al, 2005). The combinations of pencillin with ethanolic extracts of Paederia scandens and Taraxacun monlicum showed a strong bactericidal activity on two strains of S. aureus (Yang et al, 2005).…”

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“…Besides, the mentioned extract had the highest activity against C. albicans among 56 widely used dried Chinese medical plants 51 . In another investigation, ethanol extract of S. baicalensis was found to be capable of improving the in vitro antimicrobial activity of four antibiotics (penicillin G, gentamicin, ciprofloxacin, ceftriaxone) against methicillinresistant Staphylococcus aureus 52 . To conclude, the findings of the present study provided evidence with respect to the antioxidant and antimicrobial properties of S. litwinowii extracts.…”