The TOronto ThromboProphylaxis Patient Safety Initiative (TOPPS): A cluster randomised trial

Diamantouros, Artemis; Kiss, Alex; Papastavros, Tina; David, U; Zwarenstein, Merrick; Geerts, William

doi:10.1016/j.sapharm.2017.05.015

Cited by 5 publications

(5 citation statements)

References 40 publications

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“…There were 11 cluster randomized control trials, 15-25 8 interrupted time series studies, 26-33 2 randomized control trials, 34,35 2 stepped wedge studies, 36,37 and 1 nonrandomized stepped wedge study. 38…”

Section: Resultsmentioning

confidence: 99%

“…Another major source of bias was the lack of reporting on the similarity of baseline outcome measurements, identified in eight studies. 19,21,22,24,[35][36][37][38] The remaining risk of bias criteria were not fulfilled by several studies that failed to report adequately on the specifications of these criteria. All of the interrupted time series studies failed to report whether the intervention occurred independently of other changes (Table 3).…”

Section: Risk Of Biasmentioning

confidence: 99%

“…Nineteen studies (79%) reported using electronic medical records, patient records, or chart reviews to measure process outcomes. [15][16][17]19,20,[22][23][24][26][27][28][29][30][32][33][34][35][36][37] Five studies (21%) did not use electronic medical records or chart review.…”

Section: Process Measuresmentioning

confidence: 99%

“…Of these studies, 10 used electronic medical records, 15,22,26,[28][29][30][33][34][35]37 2 used electronic medical records plus chart reviews, 27,32 2 used chart reviews, 19,36 and another 3 used patient records, 20,23,24 while 1 study used chart reviews and a pharmacologic electronic database. 16 community practice studies, 34,35 aboriginal health practice, 29 and home healthcare agency study.…”

Section: Patient Record Typementioning

confidence: 99%

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Methods of Capturing Process Outcomes in Quality Improvement Trials: A Systematic Review

2022

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Section: Resultsmentioning

confidence: 99%

Section: Risk Of Biasmentioning

confidence: 99%

Section: Process Measuresmentioning

confidence: 99%

Section: Patient Record Typementioning

confidence: 99%

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Methods of Capturing Process Outcomes in Quality Improvement Trials: A Systematic Review

2022

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“…It is the unfractionated heparin that has a predominant influence on the IIa factor (thrombinfibrinogen) of the hemocoagulation cascade. And thromboprophylaxis should be started straight after the end of the surgical intervention with the prescription of non-fractional heparin and should be continued until the first injection of LMWH, which has a predominant influence on the Xa factor of the blood coagulation system [11].…”

Section: Discussionmentioning

confidence: 99%

Nonspecific Dysplasia of the Connective Tissue – A Factor of Venous Thromboembolic Complications in Endoprosthetics of Hip Joints

Venher

Herasymiuk

Kostiv

et al. 2020

IJMMR

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Background. Important part of orthopedic surgery is endoprosthetics of hip joints, which eliminates pain syndrome, restores the amplitude of movement and the support ability of lower limbs. But some complications usually take place; venous thromboembolism is leading among them. Objective. The aim of the study was to investigate endothelial dysfunction and activity of the hemocoagulation system at different levels of VTEC risks and thus to work out the strategy of thromboprophylaxis in patients with osteoarthrosis of the hip joint and femoral neck fracture combined with non-specific dysplasia of the connective tissue. Methods. 219 patients of a mean age of 64.7±3.8 years old underwent surgery. In 137 (62.1%) cases, a total cement hip replacement was performed for osteoarthritis. 82 (37.4%) patients underwent total and unipolar cement hip replacement for cervical femoral neck fractures. Results. Clinical manifestations of non-specific connective tissue dysplasia were detected in 83 (37.9%) patients that was confirmed by the laboratory determination of the level of general, bound and free oxyproline. In the postoperative period, the thrombotic process in the venous system of the inferior vena cava was diagnosed in 23 (10.5%) cases. The level of indicators of endothelium status dysfunction was much more significant in the patients in cases of nonspecific dysplasia of connective tissue. Operative intervention on the hip joint in the patients with nonspecific dysplasia of connective tissue in 11 (13.3%) cases was complicated by development of venous thrombosis. In the patients without non-specific connective tissue dysplasia, postoperative thrombosis in the system of the inferior vena cava was diagnosed in 12 (8.8%) cases. Conclusions. Patients with osteoarthrosis of the hip joint and the femoral neck fracture accompanied by the non-specific dysplasia of the connective tissue are characterized by high levels of endothelial dysfunction and increased activity of the blood-coagulation system.

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Venous thromboembolism prevention program implementation in a community oncology practice: a cohort study

Ades,

Resnick,

Barker

et al. 2024

The Lancet Regional Health - Americas

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The TOronto ThromboProphylaxis Patient Safety Initiative (TOPPS): A cluster randomised trial

Cited by 5 publications

References 40 publications

Methods of Capturing Process Outcomes in Quality Improvement Trials: A Systematic Review

Methods of Capturing Process Outcomes in Quality Improvement Trials: A Systematic Review

Nonspecific Dysplasia of the Connective Tissue – A Factor of Venous Thromboembolic Complications in Endoprosthetics of Hip Joints

Venous thromboembolism prevention program implementation in a community oncology practice: a cohort study

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