The treatment of mycotic vulvovaginitis with propionate vaginal jelly

Short-Chain Fatty Acids as a Potential Treatment for Infections: a Closer Look at the Lungs

“…This section focuses on preclinical and clinical studies of nonrespiratory infections. Thanks to their antibacterial and antifungal properties, SCFAs have been used since 1947 to successfully treat "external" infections, such as conjunctivitis (8), dermatomycosis (44), and vulvovaginitis (45). More recently, SCFAs have been studied in animal models of colitis, necrotic enteritis, and septic arthritis, among other diseases (Table 1).…”

“…Theodore and colleagues showed that propionate prevents eye infections and helps corneal ulcers to heal without causing opacity (8). Propionate was also used to treat vulvovaginitis caused by Candida spp., with symptom relief and elimination of the pathogen in almost all treated patients (45). Recently, acetic acid was used in a clinical trial of wounds infected by P. aeruginosa; the treatment shortened the healing time and eliminated the pathogen (46).…”

Fungal Infection of the Female Genital Tract

“…In severe cases, treatment is repeated during the day. Vaginal jelly ( p H 4) containing ricinoleic acid, oxyquinoline sulphate and boric acid. Vaginal cream or a pessary containing sodium propionate (Alter and others, 1947; Kantor, 1951). …”

Moliniasis vulva-vaginal

“…-Es tal vez la droga más popular para el tratamiento de moniliasis vulva-vaginal en los Estados Unidos de Norteamérica. desde el trabajo de Alter y col. (20); Kalter (21) también usando la jalea "P,ropion-Gel" (Wyeth Inc.) en enfermas embarazadas. obtuvo mejoría en sus pacientes en el 75% de los casos y cultivos negativos en el 90% después de seis semanas consecutivas al parto ; el autor aconseja aplicación nocturna de la jalea durante 2 a 3 semanas.…”