The use of complex marketing analysis and QSPR methodology for the necessity of a drug development grounding for the treatment of type 2 diabetes mellitus with increased bioavailability

Abstract

In order to guarantee qualitative medical and pharmaceutical care it is necessary for all participants of the process to provide consistent interconnected actions, including the use of modern approaches in pharmacotherapy, assessment of the urgent needs of the population in medicines (drugs), development and introduction of modern qualitative, safe and effective drugs into the market. Today, one of the key indicators in determining the population‘s need for drugs is the epidemiological indicators in a particular region and their dynamics. In recent years, the actuality of optimal and effective approaches developing in the prevention and treatment of socially significant diseases, including diabetes mellitus (DM), has been increasingly emphasized at the global level. All actions that are proposed for the development of standardized guidelines, treatment protocols, programs for on-time detection and prevention of diabetes are aimed at forming a system of measures are patient-oriented, based on understanding the patient‘s problems, lifestyle, habits, income and expenses for treatment, as well as other components associated with achieving optimal results for patients.

Monitoring of indicators of physical availibility and socio-economic affordability of metformin hydrochloride medicines

“…According to the results of earlier studies of the assortment of antidiabetic medicines by domestic and foreign scientists, it was established that metformin HCL medicines are the most prioritized and available for the pharmacotherapy of type II diabetes among pharmaceuticals of the antidiabetic pharmacological group [19][20][21][22][23][24][25][26][27][28][29][30]. However, considering the constant market changes that affect the availability of these pharmaceuticals on the Ukrainian market, as well as their price, it is relevant to conduct an analysis of the socio-economic indicators of metformin HCL medicines to meet the current needs of patients of various social groups.…”

Justification of the composition and technology of combined tablets for the treatment of type II diabetes.

“…Almost 3 % of the primary disability of the adult population in Ukraine is a consequence of diabetes. The results of the analysis of literature data on the drug therapy of diabetes indicate that over the past 5 years, the range of hypoglycemic drugs aimed at the correction of hyperglycemia, dyslipidemia, and the prevention of microangiopathy in patients with type 2 diabetes (DM II), which is one of the main medical and social problems, has expanded and economic problems of modern medicine [2,3].…”